Analysis of genetic association studies

Analysis of Genetic Association Studies is both a graduate level textbook in statistical genetics and genetic epidemiology, and a reference book for the analysis of genetic association studies. Students, researchers, and professionals will find the topics introduced in Analysis of Genetic Association Studies particularly relevant. The book is applicable to the study of statistics, biostatistics, genetics and genetic epidemiology.. In addition to providing derivations, the book uses real examples and simulations to illustrate step-by-step applications. Introductory chapters on probability and genetic epidemiology terminology provide the reader with necessary background knowledge. The organization of this work allows for both casual reference and close study. Authors are leading researchers and professors in the fields of Epidemiology and Biostatistics. This book presents crucial analysis and information for students, researchers, and professionals. Illustrations provided here represent data obtained from programs developed by the authors. INDICE: Introduction to statistics. - Population genetics. - Introduction to epidemiology. - Single-marker analysis for unmatched case-control data. - Single- marker analysis for matched case-control data. - Bayesian analysis for case-control data. - Robust procedures. - Advanced topics I. - Haplotype analysis for case-control data. - Gene- gene interaction. - Advanced topics II. - Genome-wide association studes (GWAS). - Cost -effictient two-stage designs andanalyses for GWAS. - Appendix. - References. - Index.

• ISBN: 978-1-4614-2244-0
• Editorial: Springer New York
• Encuadernacion: Cartoné
• Páginas: 414
• Fecha Publicación: 28/02/2012
• Nº Volúmenes: 1
• Idioma: Inglés