INDICE: Introduction. Chapter 1: [3,3]-Sigmatropic Rearrangement. 1. Claisen Rearrangement. 2. Ireland-Claisen Rearrangement. 3. Johnson-Claisen Rearrangement. 4. Cope Rearrangement. 5. Anionic oxy-Cope Rearrangement. 6. Palladium-catalyzed Cope Rearrangement. 7. Aza-Cope-Mannich Reaction. Chapter 2: Aldol Reaction. 1. Diastereoselective Aldol Reaction with Lithium Enolate. 2. Diastereoselective syn-Aldol Reaction. 3. Diastereoselective anti-Aldol Reaction. Chapter 3: Metal Allylation Reaction. 1. Boron Allylation Reaction. 2. Chromium Allylation Reaction. 3. Silicon Allylation Reaction. 4. Tin Allylation Reaction. Chapter 4: Stereoselective Reduction. 1. Stereoselective Reduction of -Hydroxy Ketones. 2. Diastereoselective Reduction of Chiral -Keto Sulfoxides. 3. Diastereoselective Reduction of -Keto Esters and Amides. 4. Evans-Chapman-Carreira Reduction. 5. Noyori Asymmetric Reduction. 6. Corey-Bakshi-Shibata Asymmetric Reduction. 7. Brown Asymmetric Reduction. Chapter 5: Other Reactions. 1. Deprotonation with Lithium Diisopropylamide. 2. Enantioselective Amination. 3. Diastereoselective Aldol Condensation. 4. L-Proline-catalyzed à-Aminoxylation. 5. L-Proline-catalyzed Aldol Reaction.This book presents a comprehensive overview of six-membered chair-like transition states in organic synthesis. Logically organized by reaction type, the sections focus on [3,3]-sigmatropic rearrangements, aldol reactions, metal allylation reactions, stereoselective reductions, and other reactions. Each reaction contains an introduction to the reaction type and history, a discussion of the corresponding six-membered chair-like transition state, and details of synthetic applications in natural products synthesis.
- ISBN: 978-0-470-17883-6
- Editorial: John Wiley & Sons
- Encuadernacion: Cartoné
- Páginas: 224
- Fecha Publicación: 22/02/2008
- Nº Volúmenes: 1
- Idioma: Inglés