In this first comprehensive resource to cover the application of single molecule techniques to biological measurements, the pioneers in the field deftly illustrate how to set up and interpret a single molecule experiment. Following an introduction to single molecule measurements and enzymology, Single MoleculeDynamics in Life Science considers molecular motors and mechanical propertiesbefore moving on to the applications themselves. The text's detailed discussions of studies on protein enzymes, ribozymes and nucleic acids will greatly interest biochemists, molecular biologists, biophysicists, and biotechnologists. INDICE: A Road Map to Single Molecule Dynamics Single Molecule Study for Elucidating the Mechanism used by Biosystems to Utilize Thermal Fluctuations Imaging and Molecular Motors Ion Channel Signal Transduction across the Plasma Membrane Dynamics of Membrane Receptors: Single Molecule Tracking of Quantum Dot Liganded Epidermal Growth Factor Studying Dynamics of Ligand-Receptor Complexes by Single-Molecule Techniques RNA in Cells Protein Dynamics and Interactions Two Rotary Motors of ATP Synthase Single Molecule FRET Studies of Helicasesand Holliday Junctions High-speed Atomic Force Microscopy for Nano-visualization of Biomolecular Processes Force-clamp Spectroscopy of Single Proteins
- ISBN: 978-3-527-31288-7
- Editorial: Verlag Chemie
- Encuadernacion: Cartoné
- Páginas: 336
- Fecha Publicación: 24/09/2008
- Nº Volúmenes: 1
- Idioma: Inglés