High Throughput Bioanalytical Sample Preparation: Methods and Automation Strategies

High Throughput Bioanalytical Sample Preparation: Methods and Automation Strategies, Second Edition, is the go-to resource for industrial analytical chemists and others seeking the latest techniques for optimizing sample preparation in their everyday workflow. Outlining the latest preparation techniques from around the globe, this helpful guide provides answers to questions such as: How do I automate a procedure? How do I work to reduce matrix interferences? Could I do this procedure on-line instead of in a batch manually? What sorbent materials are available in the market? How do I use a cation exchange resin? What has been published on micro-sampling techniques? What is a molecularly imprinted polymer? Can liquid-liquid extraction be used in a plate format? How do I seal microplates after elution? Can I elute analytes in tiny microliter volumes? How do I evaporate eluates in a microplate? How can I use my LEAP auto-sampler to perform sample prep? Which microplate can work with 50 microliter sample volumes? Featuring detailed coverage of the newer techniques that have emerged since the first edition published, including micro sampling and molecularly imprinted polymers, this book addresses the workflow pain points associated with extraction process efficiency, outlining exactly how to optimize productivity through enhanced method development. Combining a step-by-step approach with a thorough explanation of the technology, this new edition features 40% new content and 60% revised content, accurately and thoroughly capturing the latest developments in research since the previous edition published in 2003. Offers broad coverage of all sample preparation methods and techniques-including the latest industry developments-within bioanalysisProvides detailed 'How-To' approaches for each technique, making its applications immediately implementableAuthored by an industry analytical chemist who has more than 30 years of experience in all facets of sample preparation, drug analysis, and moreFeatures a thorough and inclusive bibliography of related publications in the field INDICE: Chapter 1: Role of Bioanalysis in Pharmaceutical Drug Development Chapter 2: Fundamental Strategies for Bioanalytical Sample Preparation Chapter 3: High Throughput Tools for Bioanalysis: Microplates Chapter 4: High Throughput Tools for Bioanalysis: Accessory Products Chapter 5: Automation Tools and Strategies for Bioanalysis Chapter 6: Protein Precipitation: High Throughput Techniques and Strategies for Method Development Chapter 7: Protein Precipitation: Automation Strategies Chapter 8: Liquid-Liquid Extraction: High Throughput Techniques Chapter 9: Liquid-Liquid Extraction: Strategies for Method Development and Optimization Chapter 10: Liquid-Liquid Extraction: Automation Strategies Chapter 11: Solid-Phase Extraction: High Throughput Techniques Chapter 12: Solid-Phase Extraction: Strategies for Method Development and Optimization Chapter 13: Solid-Phase Extraction: Automation Strategies Chapter 14: On-Line Sample Preparation: High Throughput Techniques and Strategies for Method Development Chapter 15: Micro sampling techniques

• ISBN: 978-0-444-63758-1
• Editorial: Elsevier
• Encuadernacion: Rústica
• Páginas: 750
• Fecha Publicación: 01/06/2016
• Nº Volúmenes: 1
• Idioma: Inglés