This volume will explore the latest findings in research into the genetics ofbreast and reproductive cancers, covering the epidemiological aspects of these cancers, their etiology, the effect of environment on genes and cancer etiology, and how research in this area can lead to development of preventative measures and treatments. INDICE: Recognition of Hereditary Breast and Reproductive Cancer Syndromes.- Cancer genetics in the clinic: The challenges and responsibilities of counseling women at risk .- Hereditary Breast and Ovarian Cancer Syndrome.- Modifiers of risk of hereditary breast and ovarian cancer.- Recent advances in under standing the cellular functions of BRCA1 and BRCA2.- Other hereditary breast and ovarian cancer syndromes and their genes.- Endometrial and ovarian cancer in patients with HNPCC Syndrome.- Somatic alterations and implications in breast epithelial cells.- Somatic alterations and implications in ovarian epithelial cells.- High frequency low penetrance alleles.- Host and viral genetics and risk of cervical cancer .- Estrogen metabolizing gene polymorphisms, genetic susceptibility, and pharmacogenomics.- The future of discoveries in breast and reproductive cancers: the genome and epigenetics.
- ISBN: 978-1-4419-0476-8
- Editorial: Springer
- Encuadernacion: Cartoné
- Páginas: 260
- Fecha Publicación: 01/10/2009
- Nº Volúmenes: 1
- Idioma: Inglés