Chemical analysis of antibiotic residues in food

ÍNDICE: Preface. Editors. Contributors. Chapter 1. Antibiotics: Groups and Properties (Philip T. Reeves). 1.1 Introduction. 1.2 Antibiotic Groups and Properties. 1.3 Major Groups of Antibiotics. 1.4 Restricted and Prohibited Uses of Antimicrobial Agents in Foods Animals. 1.5 Conclusions. Chapter 2. Pharmacokinetics, Distribution, Bioavailability, and Relationship to Antibiotic Residues (Peter Lees and Pierre-Louis Toutain). 2.1 Introduction. 2.2 Principles of Pharmacokinetics. 2.3 Administration, Metabolism, Distribution of Drug Classes.2.4 Setting Guidelines for Residues by Regulatory Authorities. 2.5 Definition, Assessment, Characterisation, Management and Communication of Risk. 2.6 Residue Violations, their Significance and Prevention. 2.7 Further considerations.Chapter 3. Antibiotic Residues in Food, Drinking Water, and Food Safety Regulations (Kevin J. Greenlees, Lynn G. Friedlander and Alistair Boxall). 3.1 Introduction. 3.2 Residues in Food Where is the Smoking Gun? 3.3 How Allowable Residue Concentrations are Determined? 3.4 Indirect Consumer Exposure to Antibiotics in the Natural Environment. 3.5 Summary. Chapter 4. Sample preparation: Extraction and Clean-up (Alida A. M. (Linda) Stolker and Martin Danaher). 4.1 Introduction. 4.2 Sample Selection and Pre-treatment. 4.3 Sample Extraction. 4.4Extraction Techniques. 4.5 Final Remarks and Conclusions. Chapter 5. Bioanalytical Screening Methods (Sara Stead and Jacques Stark). 5.1 Introduction. 5.2 Microbial Inhibition Assays. 5.3 Rapid Test Kits. 5.4 Surface Plasmon Resonance (SPR) Biosensor Technology. 5.5 Enzyme-Linked Immunosorbent Assay. 5.6 General Considerations Concerning the Performance Criteria for Screening Assays. 5.7 Overall Conclusions on Bioanalytical Screening Assays. Chapter 6. Chemical Analysis: Quantitative and Confirmatory Methods (Jian Wang and Sherri B. Turnipseed). 6.1 Introduction. 6.2 Single-class and Multi-class Methods. 6.3 Chromatographic Separation. 6.4 Mass Spectrometry. Chapter 7. Single Residue Quantitative and Confirmatory Methods (Jonathan Tarbin, Ross Potter, Alida A. M. (Linda) Stolker and Bjorn Berendsen). 7.1 Introduction. 7.2 Carbadox and Olaquindox. 7.3 Ceftiofur and Desfuroylceftiofur. 7.4 Chloramphenicol. 7.5 Nitrofurans. 7.6 Nitroimidazoles and their Metabolites. 7.7 Sulfonamides and their N4-Acetyl Metabolites. 7.8 Tetracyclines and their 4-epimers. 7.9 Miscellaneous. 7.10 Summary. Chapter 8. Method Development and Method Validation (Jack F. Kay and James D. MacNeil). 8.1 Introduction. 8.2 Sources of Guidance on Method Validation. 8.3 The Evolution of Approaches to Method Validation for Veterinary Drug Residues in Foods. 8.4 Method Performance Characteristics. 8.5 Components of Method Development. 8.6 Components of Method Validation. 8.7 Performance Characteristics Assessed during Method Development and Confirmed during Method Validation for Quantitative Methods. 8.8 Significant Figures. 8.9 Final Thoughts. Chapter 9. Measurement Uncertainty (Jian Wang, A

• ISBN: 978-0-470-49042-6
• Editorial: John Wiley & Sons
• Encuadernacion: Cartoné
• Páginas: 448
• Fecha Publicación: 12/08/2011
• Nº Volúmenes: 1
• Idioma: Inglés