Iron-containing enzymes: versatile catalysts of hydroxylation reactions in nature

Mononuclear iron containing enzymes are important intermediates in bioprocesses and have potential in the industrial biosynthesis of specific products. Consequently, understanding their mechanism and function is important and will assist in searches for commercial exploitation. The Editors, leaders in the field of nonheme and heme iron containing monoxygenases, have filled the book withtopical review chapters by leaders in the various sub-disciplines. It will, therefore, be of interest to a large readership including biochemists, bioinorganic chemists, inorganic chemists, physical chemists and computational chemists. INDICE: Nonheme iron(IV)-oxo oxidants in enzymes: Spectroscopic propertiesand reactivity patterns; Heme iron(IV)-oxo oxidants in enzymes: Spectroscopicproperties and reactivity patterns; Mechanism and function of taurine/ -ketoglutarate dioxygenase enzymes, an update; Mechanism and function of cysteine dioxygenase enzymes; Mechanism and function of heme peroxidase enzymes; Mechanism and function of cytochrome P450 enzymes. Biomimetic studies of mononuclear nonheme iron containing oxidants; Biomimetic studies of mononuclear porphyrin containing oxidants; Density functional calibration studies on iron-containing systems; Density functional theory studies on isomerisation reactions catalyzed by cytochrome P450 enzymes. Quantum mechanics/molecular mechanics studies ofperoxidase enzymes; Theoretical modelling of nonheme iron containing oxidants

• ISBN: 978-1-84973-181-2
• Editorial: Royal Society of Chemistry
• Encuadernacion: Cartoné
• Páginas: 415
• Fecha Publicación: 31/10/2011
• Nº Volúmenes: 1
• Idioma: Inglés