Stem Cells: An Alternative Therapy for COVID-19 and Cytokine Storm

Stem Cells: An Alternative Therapy for COVID-19 and Cytokine Storm provides mechanistic insights into the role of stem cells to combat COVID-19 outbreak and other pathologies where cytokines storm is the cause of concern for e.g., radiation exposure, multiple organ failure and sepsis. There has been an increase in number of cases of new diseases in the last decade, including mucormycosis, Zika virus, H1N1 influenza virus, among others. These diseases can be characterized by the induction of cytokine storm, which is mainly responsible for morbidity and mortality. Stem cell therapy has emerged as a potential treatment for viral diseases, including, but not limited to, COVID-19. Interestingly, clinical trials in patients with COVID-19 complications depicted faster recovery in patients post mesenchymal stem cells therapy owing to the decreased cytokines levels, anti-viral effects and regeneration of the infected tissue. Evaluates the role of MSCs to combat cytokine storm, the challenges regarding COVID-19 therapy and how they can be countered using stem cells, and the risk of opportunistic infections post COVID-19 Presents how stem cell therapy has emerged as a potential treatment for viral diseases, including, but not limited to, COVID-19 Provides a detailed understanding of the novel coronavirus, with an emphasis on therapeutic aspects INDICE: 1. Outbreak of Novel Disease2. COVID-19 Biology3. SARS-CoV-2 Associated Complications4. Current Therapeutics available against SARS-CoV-25. Opportunistic Infections and Complications Post-COVID-196. Cytokines Storms and their Implications7. Stem Cells as Therapeutics8. Effect of COVID-19 on Stem Cells and their Lineages9. Immunomodulation and Migratory Potential of Stem Cells as Therapeutics10. Significance of Clinical Trials on Stem Cells as an Alternative to Traditional Medicine11. Delimitation of Stem Cells against Key Concern Areas12. Clinical Limitation of Stem Cells Therapy13. Stem Cell Based Research and Guidelines14. Stem Cell Research and Socio-scientific Community15. Computational Approaches of Drug Development for COVID-19 and Cytokine Storm16. Conclusion

• ISBN: 978-0-323-95545-4
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 200
• Fecha Publicación: 01/06/2023
• Nº Volúmenes: 1
• Idioma: Inglés