Small-molecule inhibitors of protein-protein interactions

In this volume, the editors have collected the knowledgeable insights of a number of leaders in this field - researchers who have achieved success in addressing the difficult problem of inhibiting protein-protein interactions. These researchers describe their unique approaches , and share experiences, results,thoughts, and opinions. The content of the articles is rich, and in terms of scope ranges from generalized approaches to specific case studies. There are various focal points, including methodologies and the molecules themselves. Ultimately, there are numerous lessons to be taken away from this collection, andthe editors hope that this snapshot of the current state of the art in developing protein-protein inhibitors not only pays tribute to the past successes, but also generates excitement about the future potential of this field In this volume, the editors have collected the knowledgeable insights of anumber of leaders in this field - researchers who have achieved success in addressing the difficult problem of inhibiting protein-protein interactions. Thecontent of the articles is rich, and in terms of scope ranges from generalized approaches to specific case studies. There are various focal points, including methodologies and the molecules themselves. INDICE: Preface. Hydrogen-bonded synthetic mimics of protein secondary structure as disruptors of protein-protein interactionsSmall-molecule inhibitors of the p53-MDM2 interaction. Subject index.

• ISBN: 978-3-642-17082-9
• Editorial: Springer Berlin Heidelberg
• Encuadernacion: Cartoné
• Páginas: 174
• Fecha Publicación: 12/01/2011
• Nº Volúmenes: 1
• Idioma: Inglés