Nanotechnologies in Preventative and Regenerative Medicine demonstrates how control at the nanoscale can help achieve earlier diagnoses and create more effective treatments. Chapters take a logical approach, arranging materials by their area of application. Biomaterials are, by convention, divided according to the area of their application, with each chapter outlining current challenges before discussing how nanotechnology and nanomaterials can help solve these challenges This applications-orientated book is a valuable resource for researchers in biomedical science who want to gain a greater understanding on how nanotechnology can help create more effective vaccines and treatments, and to nanomaterials researchers seeking to gain a greater understanding of how these materials are applied in medicine. Demonstrates how nanotechnology can help achieve more successful diagnoses at an earlier stageExplains how nanomaterials can be manipulated to create more effective drug treatmentsOffers suggestions on how the use of nanotechnology might have future applications to create even more effective treatments INDICE: 1. Early Diagnostic, in situ Disease Monitoring and other Preventive Applications 1.1. Molecular basis of differentiating nanomaterial interactions between healthy and diseased cells and tissues 1.2. Self-organized functional molecular systems for targeting disease markers on the nanoscale 1.3. Organs on chips: developing advanced materials and devices for early diagnostics in preventive healthcare 1.4. Surface analysis in biology and medicine 1.5. Enabling technology development for DNA repair during nanoscale injury 1.6. Portable diagnostics for next generation drug and bioactive component delivery, imaging, tissue engineering and in vivo regeneration 2. Therapeutic and Regenerative Applications of Nanotechnologies in Medicine 2.1. Understanding the behaviour and the mechanistic basis of synthetic polymer interactions with biological milieus 2.2. Dendrimeric nanoparticles and their application in catalysis, molecular materials science and nanomedicine 2.3. Mechanistics of drug delivery to solid tumours 2.4. Developing targeting moieties for nanoparticle drug delivery therapies using biocompatible and biodegradable polymeric nanoparticles 2.5. Liposomal nanoparticle delivery systems 2.6. Nanochanneled implants for the controlled release of therapeutics 2.7. Developing advanced tissue substitutes and medical implant materials using biodegradable polymers and ceramic nanoparticles 2.8. Drug and gene delivery via ocular, nasal, and pulmonary routes of administration 2.9. Developing new techniques for mimicking ECM networks for regenerative medicine and other industrial applications 2.10. Researching 3D printing of soft functional materials and microvascular architectures for cell culture and tissue engineering 3. Theranostic Applications of Nanotechnologies in Medicine 3.1. Ultra-pH sensitive nanoparticles for tumor acidosis and lysosome imaging in theranostic medicine 3.2. Molecular assemblers and nanofactories for use in nanomedicine 3.3. Nanotechnology of spherical nucleic acids, organometallic chemistry and dip-pen lithography 3.4. Enzymatically triggered polymeric delivery systems for controlled release 3.5. Self-healing biomaterials and their theranostic applications 3.6. Development of improved diagnostic and therapeutic strategies that can detect and intervene in the early cellular dysfunction of disease 3.7. Synthetic smart, environmentally sensitive polymers and bio-derived molecules for applications in nanomedicine 4. Reigning Challenges and Vision for the Future of Nanotechnologies in Medicine 4.1. Technology side of nanotechnology: the complexity of the synergy between self-assembly, materials science, and cell-surface biochemistry 4.2. Nanomaterial therapeutic devices and the study of nanomaterial properties that lead to biocompatible and biohazardous interaction 4.3. Nanotechnologies for preventive and regenerative medicine: an emerging big picture
- ISBN: 978-0-323-48063-5
- Editorial: Elsevier
- Encuadernacion: Cartoné
- Páginas: 240
- Fecha Publicación: 01/10/2017
- Nº Volúmenes: 1
- Idioma: Inglés