Coronary Artery Disease: From Biology to Clinical Practice links the most important basic concepts of atherosclerosis pathophysiology to treatment management of coronary artery disease. Comprehensive coverage starts with the basic pathophysiologic mechanisms of the disease, including molecular and genetic mechanisms, cells interaction and inflammation. In addition, sections on novel anti-atherosclerotic therapies and a thorough understanding of the recent trends in clinical management round out this comprehensive tome that is ideal for practitioners and researchers. By summarizing this novel knowledge and changes in diagnostic algorithm and treatment options, this is the perfect reference for cardiology researchers who want a volume with the most up-to-date experimental trends in the field of atherosclerosis, for cardiologists and physicians who manage patients with atherosclerotic risk factors and established coronary artery disease, and medical students who want to learn the basic concepts of atherosclerosis. Delivers a comprehensive connection between basic pathophysiologic mechanisms and the clinical context of coronary artery diseaseProvides a focus on the most important novel evidence in the management of atherosclerosis and coronary artery diseaseIncludes sum-up tables at the end of each chapter and clinical scenarios that focus on diagnosis and treatmentConveys an understanding of upcoming, novel, experimental and clinical treatments INDICE: Chapter 1: Pathophysiology of atherosclerosis Biology of the vessel wall Endothelial function Atherosclerotic plaque Risk factors (dyslipidemia, smoking, hypertension etc.) The role of inflammation The role of oxidative stress Genetics of atherosclerosis Chapter 2: Coronary artery circulation: Basic principles Functional anatomy Myocardial oxygen consumption Regulation of oxygen transport and coronary blood flow Stable angina pectoris Acute coronary syndromes Chapter 3: Novel and experimental therapies in advance atherosclerosis Anti-inflammatory treatments Anti-oxidant treatment Gene-therapy Stem-cell therapy Diagnostic strategies-novel imaging modalities-multimodalities and hybrid techniques Novel antiplatelet agents Primary percutaneous coronary intervention Novel developments in interventional strategies
- ISBN: 978-0-12-811908-2
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 512
- Fecha Publicación: 01/10/2017
- Nº Volúmenes: 1
- Idioma: Inglés