Fundamentals of Free Radicals and Synthetic Strategies for Organic Synthesis

Free radical reactions have become a very popular and increasingly important tool in organic synthesis, due to their powerful, selective, specific, and mild reaction abilities for organic synthesis. The second edition of Fundamentals of Free Radicals and Synthetic Strategies for Organic Synthesis presents the most recent advances and useful free radical reactions for synthetic organic chemists. This new and updated second edition reviews information on all types of practical radical reactions, e.g. cyclizations, additions, hydrogen-atom abstractions, decarboxylation reactions. The book provides experimental details for the most important reactions as well as numerous references to the original literature. By covering both the fundamentals and synthetic applications it is suitable for both new and experienced researchers, chemists, biochemists, natural product chemists and graduate students. This book is the definitive guide to radical chemistry for all scientists. Introduces and reviews the use of radicals to perform synthetic transformationsIncludes practical details on the most important synthetic methodsContains numerous references to primary literatureNew edition reviews all types of practical radical reactions, including cyclizations, additions, hydrogen-atom abstractions, decarboxylation reactions INDICE: 1. Fundamentals for Free Radicals2. Functional Group Transformation3. Intramolecular Radical Cyclizations4. Intermolecular Radical Addition Reactions5. Alkylation of Aromatics and Heteroaromatics6. Intramolecular Hydrogen-Atom Abstraction7. Synthetic Uses of Free Radicals for Nucleosides and Sugars8. Barton Decarboxylation Reaction with Carboxylic Acids9. Whol-Ziegler Reaction and Fenton Reaction10. Free Radical Reactions with Metal Hydrides11. 1,2-Rearrangement of Acyloxy and Related Groups12. Stereoselective Radical Reactions13. Free Radicals Related to Biology14. Synthetic Uses of Free Radicals for Natural Products and Pharmaceuticals

• ISBN: 978-0-12-820220-3
• Editorial: Elsevier Science
• Encuadernacion: Rústica
• Fecha Publicación: 01/08/2020
• Nº Volúmenes: 1
• Idioma: Inglés