The book chapters cover different aspects of epilepsy genetics, starting with the classical concept of epilepsies as ion channel disorders. The second part of the book gives credit to the fact that by now non-ion channel genes are recognized as equally important causes of epilepsy. The concluding chapters are designed to offer the reader insight into current methods in epilepsy research. Each chapter is self-contained and deals with a selected topic of interest. Authors are the leading experts in the field of epilepsy researchBook covers the most important aspects of epilepsy Interesting for both scientists and clinicians INDICE: Genetic Heterogeneity in Familial Nocturnal Frontal Lobe Epilepsy Ortrud K. Steinlein Potassium Channel Genes and Benign Familial Neonatal Epilepsy Snezana Maljevic and Holger Lerche Mutant GABAA Receptor Subunits in Genetic (Idiopathic) Epilepsy Shinichi Hirose The Role of Calcium Channel Mutations in Human Epilepsy Antonio Gambardella and Angelo Labate Mechanisms Underlying Epilepsies Associated with Sodium Channel Mutations Ortrud K. Steinlein The Progressive Myoclonus Epilepsies Berge A. Minassian Genetics Advances in Autosomal Dominant Focal Epilepsies: Focus on DEPDC5 Stéphanie Baulac PRRT2: A Major Cause of Infantile Epilepsy and other Paroxysmal Disorders of Childhood Carlo Nobile and Pasquale Striano LGI1: From Zebrafish to Human Epilepsy John K. Cowell Morphogenesis and Timing of Genetically-Programmed Brain Malformations in Relation to Epilepsy Harvey B. Sarnat and Laura Flores-Sarnat Remind Me Again What Disease We are Studying? A Population Genetics, Genetic Analysis, and Real Data Perspective on Why Progress on Identifying Genetic Influences on Common Epilepsies has Been So Slow David A. Greenberg and William L. Stewart Monogenic Models of Absence Epilepsy: Windows into the Complex Balance between Inhibition and Excitation in Thalamocortical Microcircuits Atul Maheshwari and Jeffrey L. Noebels New Technologies in Molecular Genetics: The Impact on Epilepsy Research Ingo Helbig Epigenetic Mechanisms in Epilepsy Katja Kobow and Ingmar Blümcke
- ISBN: 978-0-444-63326-2
- Editorial: Elsevier
- Encuadernacion: Cartoné
- Páginas: 288
- Fecha Publicación: 01/09/2014
- Nº Volúmenes: 1
- Idioma: Inglés