Diabetes and Dementia provides a comprehensive overview detailing the relationship between diabetes and dementia and the future of medicine and therapeutics in this area. The chapters range from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment and prevention strategies, and round off on the application of therapeutics. The book is geared to reflect translational aspects of current science in the field, as well as in the future. A special feature is the emphasis and display of neuroimaging and neuropathology. Diabetes and Dementia, has contributions from world experts and is an invaluable international resource for clinicians and researchers in the fields of neurology, neuroscience, geriatric medicine, and endocrinology. Comprehensive overview detailing the relationship between diabetes and dementia and the future of medicine and therapeutics in this areaWritten for researchers and clinicians in neurology, neuroscience, geriatric medicine, and endocrinologyTopics ranging from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment and prevention strategies, and therapeutic applications INDICE: 1. Overview2. Diabetes, obesity and dementia - epidemiology3. Cognitive dysfunction - magnitude and trajectories4. Structural Imaging -neurodegeneration5. Structural imaging - vascular disease6. Functional imaging - connectivity and metabolism7. Dementia biomarkers in diabetes and obesity8. Microvascular disease in diabetes and dementia9. Diet, exercise, metabolism and brain10. Neuropathological insights11. Basic mechanisms - insulin resistance and signalling12. Basic mechanisms - advanced glycation13. Basic mechanisms - neuroinflammation, blood brain barrier dysfunction14. Basic Mechanisms - immune pathways15. Genetics, Epigenetics16. Therapeutics - pharmacology17. Therapeutics - non-pharmacological
- ISBN: 978-0-12-809454-9
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 200
- Fecha Publicación: 01/03/2018
- Nº Volúmenes: 1
- Idioma: Inglés