Molecular Medicine and Biomedical Research in the Era of Precision Medicine: New Technologies and Personalized Drug Therapies for Patient Care

Molecular Medicine and Biomedical Research in the Era of Precision Medicine: New technologies and personalized drug therapies for patient care provides researchers with an extensive overview of recent advances in molecular biology impacting the development of targeted therapies. It delivers insights into the pathobiological and pathogenetic mechanisms of various diseases, providing a detailed study of the latest personalized interventions to be implemented across such conditions.The book covers a range of technologies including RNA-sequencing, AI, Machine Learning, gene therapy, omics and nanotechnology, delving into their clinical applications across various diseases. It also tackles targeted treatments of different disease types including acute, chronic, infectious and noncommunicable diseases. Future perspectives are also covered.This book provides an in-depth study across molecular medicine, drug discovery and delivery, disease diagnosis and prevention, and therapeutic interventions, acting as an invaluable interdisciplinary reference for researchers across the biomedical sciences. Investigates the molecular basis and mechanisms of diseases, including cardiovascular, infectious and neurological diseasesPresents molecular-based therapeutics for personalized treatment and diagnosis of various conditionsConsiders a range of technologies in the field of biomedicine and molecular medicine, including artificial intelligence and nanotechnology INDICE: Section I: Introduction to molecular medicine, drug discovery and drug delivery, and their roles in biomedical sciences Introduction and PrefaceSection II: Technologies in biomedicine and molecular medicineA: Basic and emerging technologies1. Single-cell RNA-seq technologies in biomedical studies and their potential clinical applications2. Next-generation sequencing (NGS), OMICS and gene editing technologies: Their role in biomedical sciences3. Artificial intelligence in molecular medicine4. Role of modern scientific technologies and innovations for augmenting health care and precision in health care system5. Machine Learning in the field of health care using medical images6. Role of computer assisted prediction models in disease prevention7. Physiological studies on the usefulness of chips8. Bioinformatics as a tool for biomedical innovations9. Molecular Epidemiological approach in disease management10. Novel aspects of personalized medicines, patient care and management11. Stem cells and Gene Therapy in disease management12. Role of telemedicine in point of care treatment of patientsB: Application of technology in some diseases13. Machine learning based data modeling for heart disease prediction14. Computational biomedical sciences for renal disease management15. Impact of machine learning in the prediction and prevention of neurological diseases.16. Telemedicine and internet-based advice to pregnant and nursing mothers17. Effectiveness of telemedicine and internet-based diagnosis for the prevention of adverse drug effects (ADRs).18. Harvesting and growing of stem cells for regenerative medicine with special reference to dermal disorders19. Nanotechnology innovations for targeted delivery of multiple drugs in cancer patients20. Development of prolonged drug delivery systems for the treatment of chronic diseases21. Gold nanoparticles: A promising molecular probe for diagnostic purposes, discovery of new therapies, cure for certain cancers, as well as gene carriers and drug delivery vehicles22. Impact of circadian rhythms in neurological disorders, cardiovascular diseases, and diabetes mellitus23. Role of Omics and metabolomics in drug discovery and drug delivery in biomedical sciences24. Pharmacogenetics in drug dose adjustments in the pediatric and elderly populations25. Impact of lifestyle factors on cognitive function in older adults (> 60 yrs.) and detection by apolipoprotein E genotyping.Section III: Interventions and treatments across disease typesA: Role of microbiota in diseases26. Pivotal role of healthy gut microbiota in the prevention of non-communicable diseases (NCDs)27. Emerging role of gut microbiomes in immunomodulation and colorectal cancer28. Influence of the gut microbiomes on cardiovascular health and hypertension29. Role of probiotics, prebiotics and symbiotic in the improvement of gut microflora30. Genetic, cellular and molecular biology germane to cardiovascular ailments (e.g., coronary heart disease and stroke) and neurological diseases (e.g., dementia, Alzheimer disease) in the ageing population31. Molecular biology of chronic heart failure: Prevention and management by antioxidant and anti-inflammation foods and phytotherapies32. Therapeutic applications of human and bovine colostrum: Underlying mechanisms of actionB: Challenges and interventions in NCDs33. Environmental impact on cardiorespiratory and kidney related diseases34. Pathophysiology of coronary heart disease: Role of the renin-angiotensin and aldosterone system35. Emerging respiratory problems including chronic obstructive pulmonary disease (COPD)36. Stroke: Causes, diagnosis and management by cholesterol lowering agents and other suitable medicinesC: Challenges and interventions in infectious diseases37. Emerging and re-emerging infectious diseases and challenges ahead38. Tuberculosis: Molecular aspects in prediction, diagnosis and treatment39. Viral hepatitis: its occurrence, diagnosis and management40. Monkey pox and its impact on human health41. Prophylactic vaccination strategies for the prevention of microbial diseases with particular reference to COVID-19 on public health and health care systemSection IV: Molecular medicine and nutrition42. Clinical Nutrition in health promotion and well-being43. Influence of nutraceuticals in health promotion and disease prevention44. Biochemical, biophysical and therapeutic properties of functional foods and Mediterranean diet45. Traditional and novel fermented foods in the prevention of non-communicable diseases (NCDs)46. Clinical implications and mechanism of drug-drug and drug-food-herbal interactions???????Section V: Targeted therapies and strategies for the treatment of acute and chronic diseases47. Emerging trends in drug delivery systems: Scope and challenges48. Role of Nanotechnology in the targeted delivery of anticancer drugs49. Impact of Phamacometabolomics in new drug discovery and development of novel therapies for the management of NCDs50. Drug dose adjustment in elderly population using polypharmacy for co-morbid conditions51. Safety and efficacy assessment of new vaccines and their development52. Antibiotic resistance and development alternative therapies53. Drug regulatory requirements by the drug regulatory agencies54. Post-marketing surveillance of drugs for monitoring adverse drug reaction (ADRs)55. Ethical issues and challenges in biomedical researchSection VI: Future perspectives in the development of novel technologies in biomedicine and molecular medicine

• ISBN: 978-0-443-22300-6
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 600
• Fecha Publicación: 01/01/2025
• Nº Volúmenes: 1
• Idioma: Inglés