Nervous system injuries, including peripheral nerve injuries, brain and spinal cord injuries, and stroke affect millions of people worldwide every year. As a result of this high incidence of neurological injuries, neural regeneration and repair is becoming a rapid growing field dedicated to the new discoveries to promote structural and functional recoveries based on neural regeneration. The ultimate goal is to translate most optimal regenerative strategies to treatments of human nervous system injuries. Neural Regeneration provides an overview of cutting-edge knowledge on a broad spectrum of neural regeneration, including 1) neural regeneration in lower vertebrates, 2) neural regeneration in the peripheral nervous system, 3) neural regeneration in the central nervous system, 4) transplantation-mediated neural regeneration, and 5) clinical and translational research on neural regeneration. The contributors of this book are experts in each of their respective fields and are highly international including scientists working at different institutions in the United States, Canada, Australia and China. This valuable reference book will be useful for students, postdoctors, and basic and clinical scientists who are interested in neural regeneration research. Provide an overview of cutting-edge knowledge on a broad spectrum of neural regeneration. Highly translational and clinically-relevanceInternational authors who are leaders in their respective fieldsVivid art work making the chapters easily understood INDICE: Section I. Introduction Chapter 1. Advances and Challenges on Neural Regeneration Research Section II. Neural Regeneration in Lower Vertebrates Chapter 2. Functional Regeneration and Remyelination in the Zebrafish Optic Nerve Chapter 3. Central Nerve Regeneration in Reptiles Chapter 4. Axon Regeneration in the Lamprey Spinal Cord Section III. Neural Regeneration in the Peripheral Nervous System Chapter 5. Tissue engineering in Peripheral Nerve Regeneration Chapter 6. Brachial plexus avulsion: a model for axonal regeneration study Chapter 7. Conditions Affecting Accuracy of Peripheral Nerve Reinnervation and Functional Recovery Chapter 8. Gonadal Steroids in Regeneration and Repair of Neuromuscular Systems Section IV. Neural Regeneration in the CNS Chapter 9. Myelin-Associated Inhibitors in Axonal Growth After CNS Injury Chapter 10. The Nogo Receptor Pathway in CNS Regeneration and Therapeutic Opportunities Chapter 11. Astrogliosis and Axonal Regeneration Chapter 12. The Intrinsic Determinates of CNS Regeneration in the Central Nervous System Chapter 13. Optic Nerve Regeneration in Lower Vertebrates and Mammals: Bridging the Gap Chapter 14. Self-assembling Peptides Mediate Axonal Regeneration Chapter 15. Wnt Signaling in Spinal Cord Injury Chapter 16. Inflammation and secondary damage after spinal cord injury Chapter 17. Neuroprotection of Retinal Ganglion Cells in Glaucoma by Blocking LINGO-1 Function, or Using Nogo-66 Receptor Antagonist Chapter 18. Axonal Regeneration in the Dorsal Column Sensory Pathway Section V. Transplantation-Mediated Neural Regeneration Chapter 19. Peripheral Nerve Graft Mediated Axonal Regeneration Chapter 20. Olfactory ensheathing glial transplantation-mediated neural Chapter 21. Glial restricted precursor transplantation-mediated axonal regeneration Chapter 22. Schwann cell-mediated axonal regeneration in the CNS Chapter 23. Fetal Spinal Cord Transplantation and Axonal Regeneration: Around and Back Again Section VI. Clinical and Translational Research on Neural Regeneration Chapter 24. Spinal Cord Injury: Exercise and Clinical Trials Chapter 25. Spinal Cord Regeneration Chapter 26. Biomarkers for CNS Injury and Regeneration Chapter 27. High Content Screening Applied to Nervous System Injury: Advantages, Challenges, and Proof of Principle
- ISBN: 978-0-12-801732-6
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 464
- Fecha Publicación: 12/04/2015
- Nº Volúmenes: 1
- Idioma: Inglés