RNA and DNA editing: molecular mechanisms and their integration into biological systems

RNA and DNA Editing assembles a team of leading experts who present the latestdiscoveries in the field alongside the latest models and methodology. In addition,the authors set forth the many open questions and suggest routes for further investigation. Overall, the book serves as a practical guide for professionals in the field who need to understand the interrelationship of RNA and DNA editing with other chemical and biological processes.This book is divided into four sections, providing a clear, contextual map ofthe field: Diversification of the Proteome through RNA and DNA Editing discusses the occurrence of editing sites within transcriptomes and their distribution within individual RNAs in order to explore why nucleic acid sequences are edited instead of encoded genomically; Functional Coordination of RNA Editing with Other Cellular Mechanisms brings to the forefront why RNA and DNA editing is essential for cell survival and adaptationPredictive Studies underscores the power of computational approaches in identifying novel editing sites and predicting the biological consequences of editing at these sites; Structural Approaches presents comparative structural analyses that suggest conserved proteinfolds and implicate, in some instances, their ancient phylogenic origins as components of editing machinery.

• ISBN: 978-0-470-10991-5
• Editorial: John Wiley & Sons
• Encuadernacion: Cartoné
• Páginas: 426
• Fecha Publicación: 01/03/2008
• Nº Volúmenes: 1
• Idioma: Inglés