Biofilm eradication and prevention: a pharmaceutical approach to medical device infections

This book covers the basics of biofilm formation on medical devices, diseasesrelated to this formation, and approaches pharmaceutical researchers need to take to limit this problem. The first section deals with the development and characterization of biofilm on the surfaces of implanted or inserted medical devices. Addressed in these chapters are the questions of why biofilms form overmedical device surfaces and what triggers biofilm formation. In the second section, the author discusses biofilm-mediated chronic infections occurred in various organs (eyes, mouth, wounds) and pharmaceutical and drug delivery knowledge gained from research in these areas. The third part pharmaceutical approaches like lipid-and polymer-based drug delivery carriers for eradicating biofilm on device-related infections. Further, this section also explores the topic of novel small molecule (like iron and its complexes/metal chelators) and a quorum-sensing inhibitors to control medical biofilm formation.

• ISBN: 978-0-470-47996-4
• Editorial: John Wiley & Sons
• Encuadernacion: Cartoné
• Páginas: 448
• Fecha Publicación: 24/09/2010
• Nº Volúmenes: 1
• Idioma: Inglés