Migraine Pain Management: Current Pharmacological and Non-pharmacological Options

Migraine Management: Current Pharmacological and Non-pharmacological Options is a comprehensive guide to established, recent and ongoing pharmaceuticals and device development projects. This book provides detailed information on the historical developments of migraine pain management, druggable targets, drugs action mechanisms, drugs for acute treatment and preventive care of patients, administration routes, and alternative treatments. This is the ideal reference for academic researchers interested in anti-migraine pharmacology. It is also the perfect reference for physicians and care professionals involved in the wellbeing of migraine patients. Offers a comprehensive overview of pharmacological and alternative migraine pain treatment optionsCovers under a single volume the historical developments, current targets for drug development and delivery routesProvides insights into comorbidities and their impact in patient compliance to treatment INDICE: Part I - Foundations and historical development on Migraine Pain Management1. Introduction2. Neuroanatomy3. Historical overview of drug development and therapeutics4. Alternative therapy development5. Comorbidities and their impact on therapies6. Not all Migraine attacks are the same7. The case for nasal deliveryPart II - Druggable targets8. CGRP9. PACAP10. Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists11. Src family kinases (SFK)12. Delta opioid receptor system13. Piezo channels in peripheral trigeminal nociception14. TRPM8 antagonistsPart IIIa - Drugs - Acute Management15. Simple analgesics16. Opioids17. Ergots18. Triptans19. Lasmiditan (and the ditan class)20. Timolol21. Rimegepant22. Combination therapiesPart IIIb - Drugs - Prevention23. Tricyclic antidepressants, SNRIs, beta-blockers24. Antiseizure and other orals - gabapentin, topiramate, candesartan, flunarizine25. Onabotulinumtoxin26. Gepants27. Monoclonal antibody28. Others: Magnesium, riboflavin, Coenzyme Q10, melatoninPart IV - Administration routes29. Oral30. Upper Nasal Space vs Traditional Nasal Spray31. Inhaled32. Sub/trans-cutaneous33.I V/InfusionPart V - Alternative Management34. The role of smartphone apps (DTx)35. Traditional and herbal medicine36. Chiropractic Therapy37. Phototherapy38. Nerve stimulators39. Acupuncture40 .Other mechanical techniques41. Nutraceuticals42. MindfullnessPart VI - Summary and conclusion [Shrewsbury]Final perspectives

• ISBN: 978-0-443-24705-7
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 500
• Fecha Publicación: 01/11/2024
• Nº Volúmenes: 1
• Idioma: Inglés