Genetic Models and Molecular Pathways Underlying Autism Spectrum Disorders

Genetic Models and Molecular Pathways Underlying Autism Spectrum Disorders provides the most recent information about animal model systems that are available to study different forms of autism spectrum disorders. In addition to genetically engineered animals that uniquely model genetic forms of ASD, the volume also provides detailed information about the translational approaches to utilizing animal model systems to gain insights into human autism and developing therapeutics. Timely subject, authoritative contributors, up to date assessment of the field, and comprehensive summaries of current knowledge, gaps and future directions INDICE: 1. Introduction Anantha Shekhar 2. Overview of genetic models of ASDs Anantha Shekhar 3. Phenotypic modeling of ASD symptoms Kathryn K. Chadman 4. Molecular mechanisms of NF1 model of ASD symptoms Andre Molosh 5. Ube3a gene dosage disorders: molecular and circuit mechanisms of ASD Matthew Anderson 6. Circuit dysfunctions in ASD models Molly Maureen Huntsman 7. ERK signaling in genetic models of ASD Gary Landreth 8. Translating ASD models from bench to bedside Anantha Shekhar 9. Studying child development in genetic models of ASD Jonathan Green 10. Clinical trial methodologies for genetic forms of autism Karin Walsh

• ISBN: 978-0-444-64194-6
• Editorial: Academic Press
• Encuadernacion: Cartoné
• Páginas: 358
• Fecha Publicación: 15/11/2018
• Nº Volúmenes: 1
• Idioma: Inglés