Cancer as a metabolic disease: on the origin, management, and prevention of cancer

The book addresses controversies related to the origins of cancer and provides solutions to cancer management and prevention. It expands upon Otto Warburg's well-known theory that all cancer is a disease of energy metabolism. However, Warburg did not link his theory to the "hallmarks of cancer" and thus his theory was discredited. This book aims to provide evidence, through case studies, that cancer is primarily a metabolic disease requring metabolic solutions for its management and prevention. Support for this position is derived from critical assessment of current cancer theories. Brain cancer case studies arepresented as a proof of principle for metabolic solutions to disease management, but similarities are drawn to other types of cancer, including breast and colon, due to the same cellular mutations that they demonstrate. INDICE: Chapter 1. Images of CancerChapter 2. Confusion surrounds the origin of cancerChapter 3. Cancer ModelsChapter 4. Energetics of normal cells and cancer cellsChapter 5. Respiratory Dysfunction in Cancer CellsChapter 6. The Warburg DisputeChapter 7. Is Respiration Normal in Most Cancer Cells?Chapter 8.Is Mitochondrial Glutamine Fermentation the Missing Link in the Metabolic Theory of Cancer?Chapter 9. Genes, Respiration, Viruses, CancerChapter 10. Respiratory Injury, the retrograde response, and the origin of cancerChapter 11. Mitochondria: The ultimate tumor suppressorChapter 12. Linking Abnormalities in Growth Control, Telomerase ActivityChapter 13. MetastasisChapter 14. Mitochrondrial Respiratory Dysfunction and the Extrachromosomal Origin of CancerChapter 15. Nothing in Cancer Biology Makes Sense Except in the Light of EvolutionChapter 16. Cancer Treatment StrategiesChapter 17. Metabolic management of cancerChapter 18. Implementation of Metabolic Therapies for Cancer ManagementChapter 19. Cancer PreventionChapter 20. Case Studies and Personal Experiences in Using the Ketogenic Diet for Cancer ManagementChapter 21. Conclusions

• ISBN: 978-0-470-58492-7
• Editorial: John Wiley & Sons
• Encuadernacion: Cartoné
• Páginas: 432
• Fecha Publicación: 29/06/2012
• Nº Volúmenes: 1
• Idioma: Inglés