The Evolution of Medicinal Chemistry: Modern Approaches to Advancing Drug Discovery

The Evolution of Medicinal Chemistry: Modern Approaches to Advancing Drug Discovery describes how new technologies and approaches can be used to improve the probability of success in fulfilling the perennial goal of finding and developing new drugs. Drawing on the author's extensive experience consulting and teaching in medicinal chemistry, the book outlines ways in which medicinal chemistry is widening its remit to meet modern demands, and how modern technologies and approaches (such as compuchem, biophysical methods, and chemical biology) are facilitating this growth into new fields. Supported by numerous examples throughout, the book is a practical resource for organic-medicinal chemists, biological chemists, and pharmacologists involved in drug discovery. Presents an authoritative overview of drug discovery processes for both medicinal and non-medicinal chemists, clarifying and explaining the role of medicinal chemistry in supporting the modern drug discovery pipeline. Shows how a wider Medicinal Chemistry view is essential for anyone in an integrated drug discovery project looking to reduce costs and save timeProvides the critical success factors in the role of outsourcing in Medicinal Chemistry, helping the reader evaluate whether their project needs external help and to what extent INDICE: The Drug Discovery ProcessMedChem - History and definitions, trends and technologiesTarget ID and Validation - the Chemistry ToolboxLead Discovery - More Haystacks, the One and Only NeedleLead Optimization - Multi-Parametric FunnelingMed Chemists and the Drug Discovery WorldWhere Do We Go from Here.

• ISBN: 978-0-08-099420-8
• Editorial: Elsevier
• Encuadernacion: Rústica
• Páginas: 600
• Fecha Publicación: 01/01/2017
• Nº Volúmenes: 1
• Idioma: Inglés