Radiochemical syntheses v. 1 Radiopharmaceuticals for positron emission tomography

This book is part of a series dedicated to providing reliable methods for radiochemical reactions, including all essential information to duplicate procedures. As a first volume, it provides established, reliable synthetic methods for a large number of routinely-prepared positron emission tomography (PET) radiopharmaceuticals, commonly used in imaging for tumor studies, cardiology, and neuroscience. By giving researchers in the field necessary experimental details, the book eliminates the time-consuming process of searching journal articles and extracting pertinent details from lengthy experimental sections or supporting information INDICE: Foreword. Editorial Preface. List of Contributors. About the Editors. Abbreviations. Part 1: Fluorine-18 Labeled Radiopharmaceuticals. Chapter 1: Synthesis of [18F]Fluorodeoxyglucose ([18F]FDG) Michelle Richards and Peter J. H. Scott Chapter 2: Synthesis of [18F]Sodium Fluoride ([18F]NaF) Brian Hockley and Peter J. H. Scott Chapter 3: Radiosynthesis of 3'-Deoxy-3'-[18F]Fluorothymidine ([18F]FLT) Hartmuth C. Kolb, Henry Padgett, Steve Zigler, Jim Patanella, Fanrong Mu, Umesh Gangadharmath, Vani P. Mocharla, Peter J. H. Scott and Joseph C. Walsh Chapter 4: Synthesis of [18F]Fluoroazomycin arabinoside (18F-FAZA) Brian G. Hockley and Peter J. H. Scott Chapter 5: Synthesis of [18F]Fluoromisonidazole (1-(2-Hydroxy-3-[18F]fluoropropyl)-2-nitroimidazole, [18F]FMISO)Patrick J. Riss, Valentina Ferrari, Robbie Bielik, Roberto Canales-Candela, Rob Smith, and Franklin I. Aigbirhio Chapter 6: Synthesis of [18F]FPPRGD2 Shuanglong Liu, Frederick T. Chin, Zhen Cheng and Xiaoyuan Chen Chapter 7: Synthesis of [18F]Fluorocholine ([18F]FCH) David Kryza Chapter 8: Clinical Manufacturing of [18F]-16-a-Fluoroestradiol ([18F]FES) Piyush Kumar and John R. Mercer Chapter 9: Synthesis of N-Succinimidyl 4-[18F]Fluorobenzoate ([18F]SFB) Xia ShaoChapter 10: synthesis of 4-(2´-Methoxyphenyl)-1-[2'-(N-2''-pyridinyl)-p-[18F]fluorobenzamido]ethylpiperazine ([18F]MPPF) Marion Alvarez and Didier Le Bars Chapter 11: Synthesis of [18F]Fallypride Laurent Brichard, Valentina Ferrari, Rob Smith, and Franklin I. Aigbirhio Chapter 12: Synthesis of [18F]Fluoroethyltyrosine ([18F]FET) Y. Zhao, A. Alfteimi and M. Zuhayra Chapter 13: Synthesis of [18F]Flumazenil ([18F]FZ) Ralf Schirrmacher, Alexey Kostikov, Gassan Massaweh, Miriam Kovacevic, Carmen Wängler, Alexander Thiel Chapter 14: Synthesis of6-[18F]Fluorodopamine (6-[18F]FDA) Michael A. Channing, John L. Musachio, andJozef J. Kusmierz Chapter 15: Synthesis of 2-([18F]fluoro)-3-[(2S)-2-Azetidinylmethoxy]Pyridine ([18F]2FA) Hayden T. Ravert, Daniel P. Holt and Robert F. Dannals Chapter 16: Synthesis of [18F]-Substance-P Antagonist-receptor Quantifier ([18F]SPA-RQ) Sofie Celen, Kim Serdons, Tjibbe de Groot, Terence G. Hamill,and Guy Bormans Part 2: Carbon-11 Labeled Radiopharmaceuticals. Chapter 17: SYNTHESIS OF [11C]-Choline Chloride ([11C]CHL) Brian G. Hockley, Bradford Henderson and Xia Shao Chapter 18: Synthesis of 2-(4-N-[11C]methylaminophenyl)-6-hydroxybenzothiazole ([11C]6-OH-BTA-1; [11C]PIB) Cécile Philippe, Markus Mitterhauser and Wolfgang Wadsak Chapter 19: Synthesis of [11C]-Meta-hydroxyephedrine([11C]MHED) Filippo Lodi, Assunta Carpinelli, Claudio Malizia and Stefano Boschi Chapter 20: Synthesis of L-[methyl-11C]Methionine ([11C]MET) Amy L. Vavereand Scott E. Snyder Chapter 21: Synthesis of (+)-±-[11C]-Dihydrotetrabenazine([11C]DTBZ) Michael R. Kilbourn Chapter 22: Synthesis of [11C]Flumazenil([11C]FMZ) Roberto Canales-Candela, Patrick J. Riss and Franklin I. Aigbir

• ISBN: 978-0-470-58895-6
• Editorial: John Wiley & Sons
• Encuadernacion: Cartoné
• Páginas: 374
• Fecha Publicación: 24/02/2012
• Nº Volúmenes: 1
• Idioma: Inglés