Porous silicon has a range of properties, making it ideal for drug delivery, cancer therapy, and tissue engineering. Porous Silicon for Biomedical Applications provides a comprehensive review of this emerging nanostructured and biodegradable biomaterial. Chapters in part one focus on the fundamentals and properties of porous silicon for biomedical applications, including thermal properties and stabilization, photochemical and nonthermal chemical modification, protein-modified porous silicon films, and biocompatibility of porous silicon. Part two discusses applications in bioimaging and sensing, and explores the optical properties of porous silicon materials; in vivo imaging assessment and radiolabelling of porous silicon; and nanoporous silicon biosensors for DNA sensing and for bacteria detection. Finally, part three highlights drug loading and characterization of porous silicon materials, tumor targeting and imaging, and porous silicon scaffolds for functional tissue engineering, stem cell growth, and osteodifferentiation. With its acclaimed editor and international team of expert contributors, Porous Silicon for Biomedical Applications is a technical resource and indispensable guide for all those involved in the research, development, and application of porous silicon and other biomaterials, while providing a comprehensive introduction for students and academics interested in the field. Comprehensive review of porous silicon focusing on the fabrication and properties of this emerging materialSpecifically discusses drug delivery and orthopedic applications of porous siliconAimed at materials researchers and scientists in the biomaterials industry - particularly those concerned with drug delivery and orthopedics INDICE: Part 1 Fundamentals of porous silicon for biomedical applications: Porous silicon for biomedical applications: From conception to clinical use; Thermal stabilization of porous silicon for biomedical applications; Thermal properties of nanoporous silicon materials; Photochemical and non-thermal chemical modification of porous silicon for biomedical applications; Modifying porous silicon with self-assembled monolayers for biomedical applications; Protein-modified porous silicon films for biomedical applications; Biocompatibility of porous silicon for biomedical applications. Part 2 Porous silicon for bio-imaging and bio-sensing applications: Optical properties of porous silicon materials for biomedical applications; In vivo imaging assessment of porous silicon; Radiolabeled porous silicon for bio-imaging applications; Desorption/ionization on porous silicon (DIOS) for metabolite imaging; Porous silicon for bacteria detection; Nanoporous silicon biosensors for DNA sensing. Part 3 Porous silicon for drug delivery, cancer therapy and tissue engineering applications: Drug loading and characterization of porous silicon materials; Nanoporous silicon to enhance drug solubility; Multistage porous silicon for cancer therapy; Porous silicon for tumour targeting and imaging; Porous silicon-polymer composites for cell culture and tissue engineering applications; Porous silicon and related composites as functional tissue engineering scaffolds; Porous silicon scaffolds for stem cells growth and osteodifferentiation.
- ISBN: 978-0-85709-711-8
- Editorial: Woodhead Publishing
- Encuadernacion: Cartoné
- Páginas: 572
- Fecha Publicación: 03/02/2014
- Nº Volúmenes: 1
- Idioma: Inglés