As the global population ages, sarcopenia remains a therapeutic challenge and major public health concern. Difficulties in defining sarcopenia as a clinical phenotype remain and have hindered treatment. Sarcopenia: Molecular Mechanism and Management Strategies provides answers and guidance on this disease that has serious health consequences in terms of fractures, frailty, disability, and a diminished quality of life. Written by experts around the world, this book is for all those that care of our aging population. Presents physical, dietary, and pharmacological strategies to maintain adequate muscle mass to ensure healthy agingProvides a complete and up-to-date reference on molecular mechanisms of sarcopeniaIdentifies a clear definition of sarcopenia and presents the latest research together in one volume INDICE: 1. The definition of sarcopenia and the physical measures being associated with sarcopenia 2. Mitochondrial dysfunction linking to sarcopenia 3. The regulation of MicroRNA for sarcopenia 4. The relationship between neuromuscular junction and sarcopenia 5. The functional role of satellite cells in sarcopenic muscle 6. The molecular mechanisms of age-related anabolic resistance 7. The autophagic defect in sarcopenic muscle 8. Mitophagy system in sarcopenic muscle 9. Sarcopenia and the inflammatory cytokines 10. Skeletal muscle ECM remodeling and sarcopenia 11. Underlying mechanisms of sarcopenic obesity 12. Dysphagia in sarcopenia and cachexia 13. Under adjustment 14. Molecular mechanism of exercise for combating sarcopenia 15. Dietary approaches to maintain muscle mass 16. Pharmacological strategy for sarcopenia 17. Stem cells and sarcopenia with some translational aspect 18. Metabolic reprogramming attenuating sarcopenia
- ISBN: 978-0-12-822146-4
- Editorial: Elsevier
- Encuadernacion: Rústica
- Páginas: 350
- Fecha Publicación: 01/07/2021
- Nº Volúmenes: 1
- Idioma: Inglés