Biochemical and Molecular Pharmacology in Drug Discovery

Biochemical and Molecular Pharmacology in Drug Discovery comprises fundamental biochemical and molecular aspects of drug discovery and basic understanding of modern drug discovery approaches, along with certain key topics related to molecular pharmacology of drugs and therapeutics. The book explains the phenomena of drug-target interactions, considering different biochemical systems and cellular strategies. With the advent of technologies, current advances, and research trends move toward molecular and/or target-based drug design and discovery. Through this book, readers will gain skills and knowledge with a thorough understanding of the subject of biochemical and molecular pharmacology in a comprehensive and systematic manner. Molecular pharmacology has gained significant momentum among researchers, scientists, and academicians because of its increasing interest in drug discovery research across the globe. Molecular pharmacology involves a fundamental understanding of drug actions at the molecular level with the help of several tools and techniques of biochemical and molecular biology. Highlights the fundamentals of biochemical and molecular aspects, with reference to drug discovery researchDepicts modern drug discovery approaches such as reverse pharmacology, drug repositioning, and CADD in the context of current research updatesSummarizes recent developments in the molecular pharmacology of novel drugs/ therapeutic molecules INDICE: 1. Structure and Functions of Biomolecules2. Pharmacokinetics and Pharmacodynamics3. Overview of Drugs and Drug Targets4. Nucleic Acids as Drug Targets5. Molecular Cloning of Drug Targets6. Pharmacogenetics and pharmacogenomics in drug discovery7. Drug-Receptor Interactions8. Enzymology in Drug Discovery9. Targeting Epitranscriptomics for Novel Drug Development10. Applications of molecular pharmacology in drug discovery11. Fundamentals of drug design and discovery 12. Fundamental Approaches of Drug Discovery13. Enzyme Inhibitors: Design of Kinase Inhibitors as anticancer drugs14. Reverse Pharmacology and Drug Repositioning in Drug Discovery15. Bioinformatics and CADD Approaches in Drug Discovery16. Artificial Intelligence-based protein structure prediction and systems biology-guided smart drug screening17. Recombinant DNA Technology and Gene Therapy18. Gut-Health Pharmacology: Integrating Microbiota Insights with Natural Product Therapies19. Neuropharmacology and Neurotherapeutics: Advancing the Understanding and Treatment of Neurological Disorders20. Molecular Oncobiology and Cancer Chemotherapeutics21. Molecular Inflammopharmacology and Therapeutics22. Molecular Cardiopharmacology and Therapeutics-I23. Molecular Cardiopharmacology and Therapeutics-II24. Molecular Endocrine Pharmacology and Therapeutics25. Molecular Viral Infections and Anti-viral Therapeutics

• ISBN: 978-0-443-16013-4
• Editorial: Elsevier
• Encuadernacion: Rústica
• Páginas: 580
• Fecha Publicación: 28/06/2024
• Nº Volúmenes: 1
• Idioma: Inglés