This is a brief introduction to the emerging field of irreversible electroporation in medicine. Certain electrical fields when applied across a cell can have as a sole effect the permeabilization of the cell membrane, presumable through the formation of nanoscale defects in the cell membrane. Sometimes this process leads to cell death, primarily when the electrical fields cause permanent permeabilization of the membrane and the consequent loss of cell homeostasis, in a process known as irreversible electroporation. This is an unusual mode of cell death that is not understood yet. While the phenomenon of irreversibleelectroporation may have been known for centuries it has become only recentlyrigorously considered in medicine for various applications of tissue ablation. A brief historical perspective of irreversible electroporation is presented and recent studies in the field are discussed. The first book on Irreversible Electroporation Includes fundamental physical basics and an outlook on clinical applications Written by the leading researchers Opens new ways in cancer therapy INDICE: History of IRE.- Basic Bioelectronics.- Review of Experimental Studies on IRE of Cells.- Review of Mathematical Models of IRE of Cells.- Mathematical Models of Heat Transfer during non Thermal IRE of Tissue.- Review of experimental Studies of IRE in Tissue.- Mathematical Models of Anisotropic.- Treatment Planning.- Electrochemotherapy and IRE.- Clinical Results with IRE (prostate).- Clinical Results with IRE (Liver, Kidney, Lung).- IRE Tissue Electroporation Systems.- Food.
- ISBN: 978-3-642-05419-8
- Editorial: Springer
- Encuadernacion: Cartoné
- Páginas: 400
- Fecha Publicación: 01/01/2010
- Nº Volúmenes: 1
- Idioma: Inglés