Kainate receptors: novel signaling insights

This volume critically examines the functional actions of the kainate?type glutamate receptors (KARs). Following on from the larger body of work on the NMDA? and AMPA-type ionotropic glutamate receptors (GluRs), studies with KARs have consistently thrown up exceptions to general rules about synaptic modulation. Contributors herein provide an insight to the idiosyncracies that now almosttypify the KAR field. The fascinating insights provided in this volume serve to encourage searching mechanistic questions. Examines the functional actions of the kainate?type glutamate receptors (KARs) Provides new insights into how KARs inhibit the slow after?hyperpolarisation current Gives insights into KAR interaction with intracellular binding partners INDICE: Metabotropic Actions of Kainate Receptors in the Control of GABA Release. In the Developing Hippocampus Kainate Receptors Control the Release ofGABA from Mossy Fiber Terminals via a Metabotropic Type of Action. Localization and Functions of Kainate Receptors in the Basal Ganglia. Metabotropic Actions of Kainate Receptors in the Control of Glutamate Release in the Hippocampus. Metabotropic Actions of Kainate Receptors in the Regulation of IsAHP and Excitability in CA1 Pyramidal Cells. Kainate Receptors with a Metabotropic Signature Enhance Hippocampal Excitability by Regulating the Slow After?Hyperpolarization in CA3 Pyramidal Neurons. Metabotropic Actions of Kainate Receptors in Dorsal Root Ganglion Cells. Role of Kainate Receptors in Network Activity during Development. Kainate Receptor Modulation by Sodium and Chloride. BTB?Kelch Proteins and Ubiquitination of Kainate Receptors

• ISBN: 978-1-4419-9556-8
• Editorial: Springer US
• Encuadernacion: Cartoné
• Páginas: 128
• Fecha Publicación: 27/05/2011
• Nº Volúmenes: 1
• Idioma: Inglés