Fetal medicine: basic science and clinical practice

Fetal medicine has emerged as a separate subspecialty over the last 30 years as a result of major advances in a number of areas, in particular ultrasound imaging, cytogenetics, molecular biology and biochemistry. The widespread use of antenatal screening and diagnostic tests has led to an increased need for obstetricians to have knowledge and skills in fetal medicine. This book providesthe information that underpins training programmes in fetal medicine and integrates science and clinical disciplines in a practical and useful way. INDICE: CELL MOLECULAR AND DEVELOPMENTAL BIOLOGY 1. Early concepts and terminology2. Genomic imprinting3. Staging embryos in development4. Embryonic tissues5. Cellular mechanisms in development-6. Homeobox genes and determination of embryonic body plan7. Embryology of left-right: defects of situs in the embryo8. Development of the head9. Stem cellsTHE PLACENTA10. Implantation11. Development of the placenta and its circulation12. Placental function and materno-fetal exchange13. Materno-fetal cell traffickingFETAL PHYSIOLOGY14. Fetal physiologyEPIDEMIOLOGY15. Cochrane, meta-analyses, trials, malformation registers.ETHICS16. Ethical issues in maternal-fetal medicinePRENATAL SCREENING AND DIAGNOSIS17. Information (genetics; post-pregnancy counselling)18. Bereavement andreaction to fetal loss19. Screening for Down syndrome 20. Ultrasound screening for fetal abnormalities and aneuploidies - 1st/2nd trimester 21. Non-invasive screening (DNA, fetal cells, TCC) 22. Invasive diagnostic techniques23. Cytogenetics 24. DNA analysis25. Preimplantation genetic diagnosis26. Haemaglobinopathies27. Cystic fibrosis28. Inborn errors of metabolismDIAGNOSIS AND MANAGEMENT OF FETAL MALFORMATIONS29. CENTRAL NERVOUS SYSTEM. embryology, screening. Ultrasound diagnosis, other imaging (MRI). management (prenatal and postnatal).Future research. Long-term outcome30. HEART . Embryology, screening. Ultrasound management (prenatal-arrthymias-invasive; postnatal). Outcome - future research31. THORAX and LUNGS . Embryology, ultrasound, management, outcome32. CONGENITAL DIAPHRAGMATIC HERNIA . Embryology, experimental surgery, u/s diagnosis,aetiology, management (pre + post natal), outcome33. ABDOMEN AND ABDOMINAL WALL . Embryology, u/s diagnosis, aetiology, management (pre- + post-natal), outcome34. KIDNEYS AND URINARY TRACT. Embryology, u/s diagnosis, management (pre-+ post-natal), outcome35. SKELETAL . Embryology, aetiology, u/s diagnosis, management36. FETAL HYDROPS37. FETAL TUMOURSDIAGNOSIS AND MANAGEMENT OF OTHER FETAL CONDITIONS38. FETAL GROWTH AND GROWTH RESTRICTION . Normal growth + its control. Monitoring, biometry, diagnosis, management, FOAD39. RED CELL ALLOIMMUNIZATION . Prevention, diagnosis, management40. FETAL PLATELET DISORDERS . Prevention, diagnosis, management41. FETAL ENDOCRINE DISORDERS . Normal and abnormal endocrinology42. EARLY PREGNANCY LOSS. Diagnosis and management43. FETAL INFECTION . Types, diagnosis, management44. THE POSTMORTEM45. AMNIOTIC FLUID . Physiology, oligo-, polyhydramnios46. TWINS/MULIPLE PREGNANCY . Aetiology, chorionicity, abnormalities, screening, invasive procedures, TTTS, MFPR, SE47. IN UTERO STEM CELL TRANSPLANTATION48. FETAL GENE THERAPYTHE NEONATE49. The interface M. ChiswickAppendix: CHARTS

• ISBN: 978-0-443-10408-4
• Editorial: Churchill Livingstone
• Encuadernacion: Cartoné
• Páginas: 800
• Fecha Publicación: 27/10/2008
• Nº Volúmenes: 1
• Idioma: Inglés