Sjögren’s syndrome: diagnosis and therapeutics

Sjögren’s Syndrome: Diagnosis and Therapeutics provides a thorough, multisystemic overview of the clinical manifestations of Sjögren’s Syndrome. It contains chapters pertinent across the range of medical specialties that may encounter Sjögren’s Syndrome cases. Chapters are specialty-specific, for easy reference by the relevant medical specialist. In addition to being a diagnostic guide,Sjögren’s Syndrome: Diagnosis and Therapeutics includes a section on prognosis and outcomes of Sjögren’s Syndrome patients and provides an exhaustive therapeutic update, focused on new agents and experimental techniques. The inclusion of diagnostic/therapeutic algorithms illustrates the text with clinical photographs of the main organs involved and helps the reader to make guided diagnostic and therapeutic decisions through decision-based algorithms. A multisystemic overview of the clinical manifestations of SS, covering all medical specialties in separate, specific chapters for each organ involved assists the reader to rapidly and easily locate the symptoms that a patient with SS may present. A description of the latest diagnostic techniques, patient-reported outcome questionnaires and immunological studies will prove essential for making an early diagnosis and correctly interpreting diagnostic tests, histopathological studies and antibodies. The inclusion of a specific section centered on prognosis and outcomes of SS patients identifies the main factors associated with a poor quality of life and the prognostic factors associated with development of cancer and death. Will provide an exhaustive therapeutic update, specifically focused on new agents and experimental techniques, which will inform the reader of recent advances in the therapeutic management of SS, with special emphasis on possible future agents and the provision of therapeutic guidelines for managing the main clinical situations. INDICE: Epidemiology. Genetics and Proteomics. Immunopathogenesis. Viruses. Etiopathogenic role of B-cells. Oral involvement. Ocular involvement. Ear, nose and throat involvement. Fatigue, fibromyalgia and other general symptoms. Musculoskeletal involvement. Non-vasculitic cutaneous involvement. Vasculitis.Cardiovascular involvement. Pulmonary involvement. Raynaud phenomenon. Gastrointestinal involvement. Autoimmune liver involvement. Pancreatic involvement. Nephro-urological involvement. Central nervous system involvement. Peripheral neuropathy. Autonomic neuropathy. Endocrine involvement. Gynecological and obstetrical complications. Laboratory abnormalities. Diagnostic procedures (I). Diagnostic procedures (II). Immunological tests. Classification criteria. Measurement of chronicity and activity. Measurement of quality of life. Associationwith other autoimmune and rheumatic diseases. Cancer. Prognostic factors and survival. SS in primary care.-Treatment of sicca features. Treatment of B-celllymphoma. Classic immunosuppressive and immunomodulatory drugs. New immunosuppressive and immunomodulatory drugs. B-cell targeted therapies. Other biological therapies. Experimental therapies.

• ISBN: 978-0-85729-946-8
• Editorial: Springer London
• Encuadernacion: Cartoné
• Páginas: 633
• Fecha Publicación: 31/10/2011
• Nº Volúmenes: 1
• Idioma: Inglés