The Scientific Basis of Mpox (Monkeypox): Features, Prevention, and Treatments

The Scientific Basis of Monkeypox: Features, Prevention, and Treatments advances understanding of monkeypox, and provides a framework for future research with evidence-based and forward-looking content. Content makes use of modelling systems and current experiences derived from case studies to provide material that is cross-disciplinary, bridging interdisciplinary divides. Furthermore, consideration is given to the behavioral response to monkeypox infection including the barriers to vaccination. Content is split into 9 sections with each individual chapter containing structured content including policy and procedures, applications to new or emerging communicable diseases, a mini dictionary of terms, and summary points. Chapter contributions are from leading national and international specialists including those from world renowned institutions to provide a global perspective. The book is a perfect reference for specialists in infectious diseases, virologists, microbiologists, health scientists, public health workers, doctors, pharmacologists and research scientists. Summarizes monkeypox using evidenced based ethosProvides practical details, recommendations and suggestions for research, prevention, and treatment: from cells to policyProvides forward thinking application to new and emerging communicable diseases INDICE: Section 1 Setting the Scene and Introductory 1. Monkeypox: The clinical and epidemiological context 2. Classification of viruses: the position of monkeypox 3. Monkeypox in different parts of the world Section 2 The Biology of Monkeypox 4. The biological features of monkeypox: an overview 5. Monkeypox transmission 6. Sequencing the monkeypox virus 7. Coinfections of monkeypox with other communicable infectious Section 3 Detection and Confirmation 8. Clinical signs and symptom of monkeypox infection 9. PCR diagnosis and analysis of monkeypox virus Section 4 Behaviour and Neurology 10. Behaviour aspects of infected individuals: intention to vaccinate and isolation 11. Barriers in mass vaccination: implications for monkeypox 12. Neurologic aspects of viral diseases: a focus on monkeypox Section 5 Effects on Tissues and Organs Systems 13. Skin changes and histopathology of monkeypox 14. Proctitis in monkeypox infection Section 6 Vaccinations, Treatments and Alleviation of Symptomology 15. Vaccines against monkeypox 16. Immune prophylaxis for monkeypox infection 17. Tecovirimat, the VP37 envelope wrapping protein and potential for monkeypox 18. Brincidofovir for treating monkeypox 19. Adamantane derivatives as potential inhibitors of p37 envelope protein rof 20. Supportive care in monkeypox infectiion: mouthwashes, analgesics and antihistamines Section 7 Modelling 21. Compartmental model of monkeypox dynamics and applications to vaccination 22. Non-human primate modelling of monkeypox 23. The wild-derived inbred CAST mouse to study monkeypox virus Section 8 Case Studies 24. Case Study: Monkeypox in an individual 25. Case Study: Monkeypox and intestinal involvements: proctitis Section 9 Resources Resources for the study and investigation of monkeypox

• ISBN: 978-0-443-22123-1
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 500
• Fecha Publicación: 01/11/2024
• Nº Volúmenes: 1
• Idioma: Inglés