Features, Transmission, Detection, and Case Studies in COVID-19

Features, Transmission, Detection, and Case Studies in COVID-19 examines the effects of the virus on the body, as well as its transmission and clinical profile. This volume begins with an introduction to the virus and its pathogenesis, transmission, and avoidance, followed by sections on pulmonary and cardiovascular effects, obesity, diabetes, the liver, detection issues, and biomarkers. Vaccines and treatment are also discussed. Specific case studies covered include hypoxia, acute kidney injury, pneumonia, and neurological effects. This volume is relevant for all clinicians and scientists working to ensure the best outcomes for patients with COVID-19. Discusses COVID-19 biology, including pathogenesis and transmissionDescribes systemic issues caused by COVID-19, including cardiovascular effects and loss of taste and smellOutlines detection methods, biomarkers associated with severity, and disease outcomesFeatures individual chapter introductions, summaries, and case studies to provide comprehensive descriptions of COVID-19 symptoms and effectsContains chapters with key facts, dictionary of terms, summary points, applications to other areas pertinent to each chapter, and policies and procedures INDICE: Preface Section A: SARS-CoV-2 and COVID-19: Introductory chapters and setting the scene 1. Coronavirus disease 2019 (COVID-19) pandemic in context: Systemic effects 2. Early warning of SARS-CoV-2 infection 3. Mobile phones and their use to study dynamics of the COVID-19 pandemic Section B: Structure, transmission and avoidance 4. Cis regulatory elements: A novel communication route between the host cell and the SARS-CoV-2 genome 5. SARS-CoV-2 ORF8: Structure, evolution, molecular function, and its contribution to thepathogenicity of the virus 6. SARS-CoV-2 spike protein binding ligands and its application in COVID-19 therapeutics 7. SARS-CoV-2 bulldozes the autophagy pathway and unhinges mitochondrial quality controlthereby driving neurodegeneration-A hypothesis 8. The Omicron variant of SARS-CoV-2 9. Monitoring SARS-CoV-2 spread in hospitals 10. Computational analysis of mutations in SARS-CoV-2 variants spike protein and proteininteractions 11. Airborne transmission of SARS-CoV-2 12. Reducing transmission of SARS-CoV-2 with face masks: Its potential protective effects 13. Digital twin of ventilation system against COVID-19 transmission and infection risk 14. Pets and SARS-CoV-2: What is their role in the epidemiology of the disease? 15. SARS-CoV-2 transmission in dental practice 16. SARS-CoV-2 compared with influenza and respiratory syncytial virus in terms of verticaltransmission 17. Reducing droplets and aerosols in the surgical setting and applications to the COVID-19pandemic 18. SARS-CoV motion dynamics: Linking in droplet size 19. Ventilation and airborne particles in classrooms: Implications for the COVID-19 pandemic 20. Indoor transmission of the SARS-CoV-2 virus through aerosols emitted by e-cigarettes Section C: Impact and effects 21. The Impact of COVID-19 on first responders 22. COVID-19 and suspected drug-induced liver injury 23. Pulmonary fibrosis in COVID-19 24. The effect of SARS-CoV-2 infection on cancer: Clinical correlation andpotential pathological mechanism 25. Severe SARS-CoV-2, plateletendothelium interactions, and cardiovascular injury 26. Cardiometabolic syndrome and COVID-19: Pathophysiological aspects 27. COVID-19 and type 1 and 2 diabetes: An overview 28. COVID-19 and older adults: An overview 29. COVID-19 and male fertility 30. COVID-19 and obesity: An overview Section D: Treatments, strategies, and vaccines 31. COVD-19 vaccines and their impact: An overview 32. Exploring the promise of COVID-19 vaccines: A review of preclinical studies 33. Drugs actively being investigated for use in COVID-19 34. The biology of neutralizing antibody therapy with REGEN-COV 35. The intensive care unit and percutaneous tracheostomy in patients with coronavirus disease2019 36. Cardiac effects of drugs and vaccines used to treat and prevent COVID-19 37. COVID-19 pandemic and isolation: Impact on sleep 38. Strategies in the COVID-19 pandemic: Disinfection of gloved hands 39. In silico studies on established antivirals on SARS-CoV-2 RNAdependent RNA polymerase 40. The COVID-19 cytokine storm and its immunomodulatory treatment 41. Safety and efficacy of nebulization for reducing the intensity of viral load and clinical manifestations in patients with COVID-19 Section E: Detection and biomarkers 42. Bronchoalveolar lavage (BAL) and use in detection of SARS-CoV-2 43. SARS-CoV-2 testing and vaccination among people who use drugs 44. Homocysteine as a biomarker in COVID-19 45. Assessment of smell and taste in COVID-19 46. S-gene analysis: RT-PCR and Sanger sequencing applied to SARS-CoV-2 virus 47. False-negative results in screening for SARS-CoV-2 48. Sample pooling and SARS-CoV-2 assays 49. Biomarkers of invasive mechanical ventilation in obesity and metabolic syndrome in patientswith COVID-19 Section F: Case studies with mini review 50. Hypoxia and heart-lung interactions in COVID-19: The significance of right heart dysfunction and shunt 51. Ulnar nerve dysfunction as COVID-19 sequelae 52. Case study: Coronavirus disease 2019 and acute kidney injury 53. Case study: The detection and treatment of a pneumothorax in a patient with coronavirus disease 2019 pneumonia 54. Proposal and demonstration of a survey method for the prevention of airborne transmission: Case studies in healthcare and welfare facilities Section G: Resources 55. Recommended resources for the features, transmission, and detection of coronavirus disease2019 (COVID-19)

• ISBN: 978-0-323-95646-8
• Editorial: Academic Press
• Encuadernacion: Cartoné
• Páginas: 694
• Fecha Publicación: 28/06/2024
• Nº Volúmenes: 1
• Idioma: Inglés