Biological interactions on materials surfaces: understanding and controlling protein, cell, and tissue responses

Success or failure of biomaterials, whether tissue engineered constructs, joint and dental implants, vascular grafts, or heart valves, depends on molecular-level events that determine subsequent responses of cells and tissues. This book presents the latest developments and state-of-the-art knowledge regarding protein, cell, and tissue interactions with both conventional and nanophase materials. Insight into these biomaterial surface interactions will play a critical role in further developments in fields such as tissue engineering, regenerative medicine, and biocompatibility of implanted materials and devices. With chapters written by leaders in their respective fields, this compendium will be the authoritative source of information for scientists, engineers, and medical researchers seeking not only to understand but also to control tissue-biomaterial interactions. Provides a comprehensive, single source of authoritative information on protein/cell/tissue-biomaterial interactions Covers both conventional and nanophase materials, including functionalized materials Includes a variety of cell types and functions Will appeal to a broad audience with an interest in understanding and controlling surface interactions of biomedical materials INDICE: Proteins (blood, extracellular matrix, growth factors, and cytokines): Experimental. Computational.- Cell functions: Osteoblasts. Chondrocytes. Endothelial cells. Keratinocytes. Hepatocytes. Neurons. Stem cells.- Conventional versus nanophase materials: Topography. Chemistry. Energetics. Patterning.- Functionalized materials: Chemical functional groups/polyelectrolytes. Mineral. Peptides. Growth factors.

• ISBN: 978-0-387-98160-4
• Editorial: Springer
• Encuadernacion: Cartoné
• Páginas: 720
• Fecha Publicación: 01/05/2009
• Nº Volúmenes: 1
• Idioma: Inglés