Prostate cancer: signaling networks, genetics, and new treatment strategies

Award winning authors present a comprehensive review of new perspectives in prostate cancer research and open up new directions in the clinical management of prostate cancer. In, ‘Prostate Cancer: Signaling Networks, Genetics, and New Treatment Strategies’, the authors focus on the biology, genetics, molecularsignaling networks in the disease process, and recent advances in the treatment of prostate cancer. This state-of-the-art title provides key insights into cutting edge advances in prostate cancer research, such as laparoscopic radical prostatectomy, and offers a critical evaluation and discussion of opportunities for development of novel therapies for prostate cancer. Clinical trials that have not been covered or evaluated in any other books currently available are also discussed. Invaluable to physicians and researchers, ‘Prostate Cancer:Signaling Networks, Genetics, and New Treatment Strategies’ provides a comprehensive translational resource. Comprehensive, with up-to-date reviews on all aspects of biology and treatment of prostate cancer INDICE: From the contents Histopathology and Molecular Biology of ProstateAtrophy: A Lesion Associated with Inflammation, PIN, and Prostate Cancer.- Epigenetic Gene Silencing in Prostate Cancer.- Inherited Genetic Changes in Prostate Cancer.- Prostate Molecular Oncogenesis: Gene Deletions and Somatic Mutations.- Somatic Genetic Changes in Prostate Cancer: Androgen Receptor Alterations.- Androgen Receptor in Prostate Cancer Progression.- Epigenetic Modification and Acetylation of Androgen Receptor Regulate Prostate Cellular Growth.- Estrogen Receptor Alpha and Beta in the Regulation of Normal and Malignant Prostate Epithelium.- Estrogen Action in Normal Prostate Epithelium and in Prostate Cancer.- Hypoxia Inducible Factor 1 and Angiogenesis in Prostate Cancer.- Signal Transduction by the Ras – MAP Kinase Pathway in Prostate Cancer Progression.- Transcription Factors Stat5 and Stat3: Survival Factors for Prostate CancerCells.- Role of PI3K-Akt and PTEN in the Growth and Progression of Prostate Cancer.

• ISBN: 978-1-58829-741-9
• Editorial: Humana Press
• Encuadernacion: Cartoné
• Páginas: 455
• Fecha Publicación: 01/01/2008
• Nº Volúmenes: 1
• Idioma: Inglés