Handbook of Pharmacogenomics and Stratified Medicine provides readers with a translational resource for study design, interpretation of primary literature, and addressing patient queries so researchers and practitioners alike can gain insight into the practical aspects of pharmacogenomics. Using a problem-based approach, the book examines lessons learned from successes and failures in the science, providing an overview of the tools available and their appropriate application. This is especially helpful for research proposals and grant writing. Pharmacogenomics incorporates pharmacology and genomics to create a new field of health care technology that is complex and multifaceted. It addresses the control of genetic diversity in patients when they are taking medications. This application studies the toxic elements and levels as well as overall effectiveness. It also helps to develop better drugs with fewer side effects, and more efficient delivery systems. Beyond genetics studies, pharmacogenomics utilizes the whole genome to bring forth new medical breakthroughs, and assesses widely used drugs for possible additional therapeutic uses. Provides clinical researchers with practical information beyond their focused areas of research, which is important for grant writing and writing scientific reportsContains an international perspective of bench-to-bedside practices, which provides readers with practical information for expanding global clinical trialsTeaches investigators about the practical implementation of concepts and techniques to achieve translational results INDICE: Handbook of Pharmacogenomics and Stratified Medicine includes 46 chapters within the following sections: I. Introduction II. Basic genetics III. Experimental and discovery platforms IV. Statistics, Bioinformatics, and Databases V. Clinical Trials VI. Fundamental pharmacogenomics VII. Applications in therapeutics VIII. Implementation and regulatory IX. Global perspective
- ISBN: 978-0-12-386882-4
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 1100
- Fecha Publicación: 12/06/2014
- Nº Volúmenes: 1
- Idioma: Inglés