Mitochondria, the power plants of eukaryotic cells, are best known for the generation of adenosine triphosphate (ATP), the universal cellular energy currency of the cell, and the synthesis of different essential components. Mitochondrial dysfunction is known to lead to various degenerative disorders, disease, and aging. The Mitochondrion in Aging and Disease works to unravel the processes leading to mitochondrial impairments and of pathways involved in mitochondrial quality control and their impact on health and aging will be addressed. Reviews current topics of interestWritten by experts in the field INDICE: The Mitochondrial Free Radical Theory of AgingGustavo BarjaMitochondrial DNA Mutations in AgingKonstantin Khrapko and Doug TurnbullMathematical Models of Mitochondrial Aging and DynamicsAxel Kowald and Edda KlippMitochondrial Dynamics in Aging and DiseaseJürgen Bereiter-HahnThe Retrograde Response - A Conserved Compensatory Reaction to Damage from Within and from WithoutS. Michal JazwinskiMitochondrial Acetylation and Genetic Models of Parkinson's DiseaseGeorg Auburger, Suzana Gispert and Marina JendrachMitochondrial Dysfunction: Cause and Consequence of Alzheimer's DiseaseKristina Friedland-Leuner, Carola Stockburger, Isabel Denzer, Gunter P. Eckert and Walter E. MüllerMitochondria in Cancer: Why Mitochondria are a Good Target for Cancer TherapyLan-Feng Dong and Jiri NeuzilEstrogen and Mitochondria Function in Cardiorenal Metabolic Syndrome Guanghong Jia, Annayya R. Aroor and James R. SowersAdvances in Development of Rechargeable Mitochondrial AntioxidantsAlexander N. Lukashev, Maxim V. Skulachev, Victoria Ostapenko, Alla Yu. Savchenko, V. V. Pavshintsev and Vladimir P. Skulachev
- ISBN: 978-0-12-394625-6
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 310
- Fecha Publicación: 01/09/2014
- Nº Volúmenes: 1
- Idioma: Inglés