Functional selectivity of G protein-coupled receptor ligands: new opportunities for drug discovery

In Functional Selectivity of G Protein-Coupled Receptors expert neuroscientists and pharmacologists review the work that demonstrated the existence of functional selectivity, placed it within a theoretical framework, and provided a mechanistic basis for the phenomenon. This exciting, comprehensive, and future-oriented volume includes chapters that focus on theoretical and mechanistic aspects of functional selectivity and that cut across subfamilies of GPCRs. Additional chapters focus on subfamilies of therapeutically relevant receptors where there is considerable evidence of ligand functional selectivity. Accessibleand authoritative, Functional Selectivity of G Protein-Coupled Receptors is avaluable educational tool and reference source for students and scientists interested in drug development, chemical biology, and GPCR function.

• ISBN: 978-1-60327-334-3
• Editorial: Humana
• Encuadernacion: Cartoné
• Páginas: 235
• Fecha Publicación: 01/04/2009
• Nº Volúmenes: 1
• Idioma: Inglés