The BMT Data Book is an essential guide to the data, outcome studies and complex decision-making processes involved in blood and marrow stem cell transplantation. Organized according to types of diseases and procedures, it contains more than hundred tables, figures and algorithms that reflect up-to-date research and give guidance on the choices between stem cell versus bone marrow transplantation, autologous versus allogeneic transplantation, and conventional versus experimental treatments. This new edition summarizes research of the last 5 years and gives mature data for all established indications, such as acute myeloid leukemia, myelodysplastic syndromes, Hodgkin's and Non-Hodgkin's lymphomas. In addition, controversies and new indications - like renal cell cancer and autoimmune disorders - are discussed plus new drugs and therapies, new stemcell sources (cord blood), new transplant protocols (reduced-intensity conditioning), and a guide to electronic databases. Includes indications, original data and survival curves for each disorder to give clinicians a quick referencewhen making treatment decisions. Includes practical 'how to' guidelines to treat patients in the transplant unit. Includes basic science on cells to enhance understanding of the science behind stem cell and bone marrow transplant INDICE: Preface; Introduction; Part I. Basic Science: 1. Basic science; Part II. Hematologic Malignancies: 2. Therapeutic decision making in BMT/SCT foracute myeloid leukemia; 3. Therapeutic decision making in BMT/SCT for acute lymphoblastic leukemia; 4. Therapeutic decision making in BMT/SCT for chronic myeloid leukemia and other myeloproliferative syndromes; 5. Therapeutic decision making in BMT/SCT for chronic lymphatic leukemia; 6. Therapeutic decision making in BMT/SCT for myelodysplasia; 7. Therapeutic decision making in BMT/SCT for non-Hodgkin's lymphoma; 8. Therapeutic decision making in BMT/SCT for Hodgkin's lymphoma; 9. Therapeutic decision making in BMT/SCT for multiple myeloma; 10. Therapeutic decision making in BMT/SCT for amyloidosis; Part III. Solid Tumors: 11. Therapeutic decision making in SCT for breast cancer; 12. Therapeutic decision making in BMT/ SCT for non-seminomatous germ cell tumor of testis(nsgct); 13. Therapeutic decision making in SCT for renal cell cancer; 14. Therapeutic decision making in SCT for soft tissue sarcomas; Part IV. Non-malignant Disorders: 15. Therapeutic decision making in BMT/SCT for severe aplastic anemia; 16. Therapeutic decision making in BMT/SCT for congenital immunodeficiencies; 17. Therapeutic decision making in BMT/SCT for hemoglobinopathies; 18.Therapeutic decision making in BMT/SCT for autoimmune disorders; Part V. Practical Aspects and Procedures: 19. Practical aspects, including conditioning protocols and haploidentical transplantation; 20. Cord blood transplantation; Part VI. Complications: 21. Patho-biology of Graft-versus-host disease; 22. Diagnosis and treatment of graft-versus host disease; 23. Infectious complications; 24. Organ-related and miscellaneous complications; Part VII. The BMT/SCT Pharmacopoeia: 25. The BMT/SCT pharmacopoeia; Part VIII. HLA-testing and Laboratory Medicine: 26. HLA-testing and laboratory medicine: Appendix: Guide to the internet and other databases; Index
- ISBN: 978-0-521-71100-5
- Editorial: Cambridge University Press
- Encuadernacion: Rústica
- Páginas: 544
- Fecha Publicación: 26/02/2009
- Nº Volúmenes: 1
- Idioma: Inglés