Metabolic Syndrome: From Mechanisms to Interventions

Metabolic Syndrome: From Mechanisms to Interventions covers all aspects of this complex and multifactorial disease, providing a cutting-edge understanding of the problem of MetS, with a particular focus on its prevention and clinical management. The book discusses practical implementable approaches to its reversal in clinical practice, encompassing the entire spectrum of MetS, from molecular understanding to clinical therapeutics and prevention. This book is a valuable resource for clinicians in multiple specialties, including endocrinologists, diabetologists, hepatologists, gynecologists and researchers in related fields who need a deep understanding of the full range of scientific and clinical aspects of metabolic syndrome. Presents a holistic, preventative strategy involving each and every aspect of metabolic syndrome, from pathophysiologic to clinical management Discusses recent research on the role of inflammation, adipokines and myokines in metabolic syndrome Includes cutting-edge information on the impact of bariatric surgery and role of gut microbiota in MetS Provides flowcharts and diagrams to simplify pathophysiologic aspects and their association between risk factors INDICE: Section 1: Introduction to Metabolic Syndrome 1. Beyond the Metabolic Syndrome: Adverse Lifelong Influences Emanating From Insulin Resistance On The Aging Process In Non-Diabetics 2. Metabolic syndrome- is it a disease or a risk factor for other disorders? 3. Intrauterine malnutrition and future risk of Metabolic Syndrome 4. Intervening at the stage of metabolic syndrome to prevent type 2 diabetes- is it justified? 5. Dietary fats and Metabolic Syndrome: How strong is the association? 6. Metabolic Syndrome needs treatment but with lifestyle interventions alone Section 2: Epidemiology of Metabolic Syndrome 7. Epidemiology of Metabolic Syndrome: Global Scenario 8. Epidemiology of Metabolic Syndrome in South and South East Asians 9. Barker's Hypothesis and Metabolic Syndrome 10. Metabolic syndrome in Australian aborigines Section 3: Pathogenesis and pathophysiology of Metabolic Syndrome 11. Diet in the pathogenesis of metabolic syndrome: Role of Sugar, salt and fat 12. Vitamin D deficiency and metabolic syndrome - Is there a causality? 13. Role of inflammation in the pathogenesis of Metabolic Syndrome 14. Role of oxidative stress in the pathogenesis of Metabolic Syndrome 15. Mitochondrial dysfunction and Metabolic syndrome 16. The entero-insular axis and metabolic syndrome 17. Type I interferons in metabolic syndrome 18. Immunometabolism, an emerging subspecialty of Metabolic Syndrome 19. Pathophysiology of metabolic syndrome: current concepts 20. Role of Circadian rhythms in Metabolic Syndrome 21. Ectopic fat distribution and its role in Metabolic Syndrome 22. The role of genetic and epigenetic factors in familial clustering of metabolic syndrome 23. High carbohydrate diet in the pathogenesis of Metabolic Syndrome 24. Endocrine disruptors in the pathogenesis of metabolic syndrome 25. Autoimmunity and Metabolic Syndrome Section 4: Metabolic Syndrome - multisystemic manifestation 26. The burden of atherosclerotic cardiovascular disease in metabolic syndrome 27. Mechanisms of atherosclerosis in metabolic syndrome 28. NAFLD, the hepatic manifestation of metabolic syndrome 29. Obesity associated hypogonadism - a growing concern in metabolic syndrome 30. Sleep apnea - A cause or a consequence of Metabolic Syndrome? 31. The metabolic syndrome in psychiatry 32. Renal manifestations of Metabolic Syndrome: The link between obesity and chronic kidney disease 33. Unraveling neuropathic manifestations of metabolic syndrome: role of corneal confocal microscopy 34. Metabolic Syndrome and Periodontitis: pathophysiologic links and clinical implications 35. Metabolic Syndrome and Bone Health 36. Insulin resistance and the risk of Osteoporosis 37. Glucagon and Metabolic Syndrome Section 5: Clinical assessment of Metabolic Syndrome 38. Measures of adiposity- from BMI to Waist circumference to neck circumference to body fat 39. The Role of Prediabetes in the Metabolic Syndrome 40. Assessment of insulin resistance: from the bench to bedside Section 6: Management of Metabolic Syndrome 41. Dietary interventions to combat obesity and Metabolic Syndrome 42. Role of precision diet and intermittent fasting in the management of metabolic syndrome 43. Nutritional and Cognitive interventions to reduce cardiovascular risk in Metabolc Syndrome 44. Role of exercise in the prevention and management of Metabolic Syndrome 45. Should Vitamin D be used to treat Metabolic Syndrome? 46. Pharmacologic therapies in Metabolic syndrome with special reference to NAFLD 47. Role of newer anti-diabetes drugs in prediabetes: A systematic review 48. Management of Insulin resistance in PCOS 49. The role of bariatric surgery in the management of metabolic syndrome 50. Anti-inflammatory interventions to mitigate cardiovascular risk in metabolic syndrome 51. Management of new onset dysglycemia in transplant recipients 52. Prevention of Type 2 diabetes in Metabolic Syndrome: Role of the geneticist 53. Managing Metabolic Syndrome in a general practice setting 54. Dietary interventions to reduce cardiovascular risk in Metabolic Syndrome 55. Management of Lipid Abnormalities in Metabolic Syndrome Section 7: Metabolic Syndrome in children and adolescents 56. Overview of metabolic syndrome in children and adolescents 57. Overview of metabolic syndrome in children and adolescents: Indian perspective 58. Metabolic syndrome in children and adolescents: Does ethnicity matter? 59. NAFLD in children and adolescents 60. PCOS in adolescents: Role of insulin resistance 61. The inter relationship between polycystic ovary syndrome (PCOS) and metabolic syndrome 62. Dietary interventions to improve cardiometabolic health outcomes in children and adolescents Section 8: Metabolic Syndrome: Controversies to consensus 63. Metabolic Syndrome -are our definitions fit for purpose? 64. Metabolic Syndrome: treat the whole or address each part? 65. Metabolic Syndrome and cancer risk Section 9: Areas for future research 66. Assessment of abdominal obesity: to measure visceral fat, subcutaneous fat or both? 67. Obesity-mediated insulin resistance in target tissues: Role of adipokines, hepatokines and myokines 68. Can bariatric surgery cure metabolic syndrome? 69. Gut microbiota and metabolic syndrome: what's new? 70. COVID19 and metabolic syndrome - an unholy alliance 71. MicroRNA modulation in metabolic syndrome: a novel insight in cardiometabolic disease 72. Role of artificial intelligence in tackling the metabolic syndrome pandemic 73. Glucose handling by the brain and its impact on metabolic syndrome 74. Impact of Hypoglycemia on cardiovascular risk in metabolic syndrome 75. Dietary interventions to combat obesity in metabolic syndrome- role of time restricted eating

• ISBN: 978-0-323-85732-1
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 500
• Fecha Publicación: 01/10/2022
• Nº Volúmenes: 1
• Idioma: Inglés