Anti-angiogenesis Strategies in Cancer Therapeutics provides a detailed look at the current status and future directions in the discovery and development of novel anti-angiogenesis strategies in oncology. This book highlights the different mechanisms involved in the modulation of angiogenesis, including inflammation, thrombosis, and microRNA, and shows how nanotechnology can further enhance the potential of existing and new anti-angiogenesis approaches. Written for industry scientists, researchers, oncologists, hematologists, and professors and students in the field, this comprehensive book covers all aspects of anti-angiogenesis strategies and their differences. Covers important preclinical models and clinical trials in the discovery and development of novel anti-angiogenesis agentsReviews FDA-approved anti-angiogenesis agentsIllustrates the value of nanotechnology in improving the utility of anti-angiogenesis agentsOffers insight into the development of novel anti-angiogenesis agents and future direction in this area INDICE: Role of Angiogenesis and lymphogenesis in Cancer (tumor growth, Invasion, metastasisRole of Angiogenesis and anti-angiogenesis in hematological malignancies (acute / chronic leukemia, lymphoma, myelodysplastic syndromes, myeloproliferative neoplasms)The interface between Thrombosis-Inflammation and Angiogenesis Micro RNA and Angiogenesis modulation Preclinical discovery and development of different Pharmacological anti-angiogenesis agentsDifferences among different anti-angiogenesis strategies (Mechanisms of actions)Naturally Occurring Anti-angiogenesisClinical trials with anti-angiogenesis agents: Approved agentsAngiogenesis Biomarkers and Impact on personalized managementEfficacy of Anti-VEGF therapy in cancerNanotechnology in enhancing the utility of anti-angiogenesis agents - Combinations with other anti-cancer agentsMulti-targeted anti-angiogenesis therapy in cancerCombination of anti-angiogenesis and chemotherapeuticsNanotechnology in enhancing the utility of anti-angiogenesis agents - Combinations with other anti-cancer agentsNano-targeted anti-angiogenesis agents in cancer detectionFuture Directions
- ISBN: 978-0-12-802576-5
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 304
- Fecha Publicación: 16/12/2016
- Nº Volúmenes: 1
- Idioma: Inglés