Arene Chemistry: Reaction Mechanisms and Methods for Aromatic Compounds

Organized to enable students and synthetic chemists to understand and expand on aromatic reactions covered in foundation courses, the book offers a thorough and accessible mechanistic explanation of aromatic reactions involving arene compounds.     Surveys methods used for preparing arene compounds and their transformations     Connects reactivity and methodology with mechanism     Helps readers apply aromatic reactions in a practical context by designing syntheses     Provides essential information about techniques used to determine reaction mechanisms INDICE: Part 1. Electrophilic Aromatic Substitution .1. Electrophilic Aromatic Substitution. Mechanism (Douglas A. Klumpp) .2. Friedel–Crafts Alkylation of Arenes in Total Synthesis (Gonzalo Blay, Marc Montesinos–Magraner and José R. Pedro) .3. Catalytic Friedel–Crafts Acylation Reactions (Giovanni Sartori, Raimondo Maggi, and Veronica Santacroce) .4. The Use of Quantum Chemistry for Mechanistic Analyses of SEAr Reactions (Tore Brinck and Magnus Liljenberg) .5. Catalytic Enantioselective Electrophilic Aromatic Substitutions (Marco Bandini) .Part 2. Nucleophilic Aromatic Substitution .6. Nucleophilic Aromatic Substitution.  An Update Overview (Michael R. Crampton) .7. Theoretical and Experimental Methods for the Analysis of Reaction Mechanisms in SNAr Processes. Fugality, Philicity and Solvent Effects (Renato Contreras, Paola R. Campodónico, and Rodrigo Ormazábal–Toledo) .8. Asymmetric Nucleophilic Aromatic Substitution (Anne–Sophie Castanet, Anne Boussonnière and Jacques Mortier) .9. Homolytic Aromatic Substitution (Roberto A. Rossi, María E. Budén, and Javier F. Guastavino) .10. Radical–Nucleophilic Aromatic Substitution (Roberto A. Rossi, Javier F. Guastavino and María E. Budén ) .11. Nucleophilic Substitution of Hydrogen in Electron–Deficient Arenes (Mieczys³aw M¹kosza) .Part 3. Aryne Chemistry .12. The Chemistry of Arynes. An Overview (Roberto Sanz and Anisley Suárez) .Part 4. Reduction, Oxidation and Dearomatization Reactions .13. Reduction/Hydrogenation of Aromatic Rings (Francisco Foubelo and Miguel Yus) .14. Selective Oxidation of Aromatic Rings (Oxana A. Kholdeeva) .15. Dearomatization Reactions. An Overview (F. Christopher Pigge) .Part 5. Aromatic Rearrangements .16. Aromatic Compounds via Pericyclic Reactions (Sethuraman Sankararaman) .17. Ring–Closing Metathesis: Synthetic Routes to Carbocyclic Aromatic Compounds using Ring– .18. Aromatic Rearrangements in which the Migrating Group Migrates to the Aromatic Nucleus. An Overview (Timothy J. Snape) .Part 6. Transition Metal Mediated Coupling .19. Transition Metal Mediated Carbon–Carbon Cross Coupling (Anny Jutand and Guillaume Lefèvre) .20. Transition–Metal–Mediated Carbon–Heteroatom Cross–Coupling (C–N, C–O, C–S, C–Se, C–Te, C–P, C–As, C–Sb and C–B Bond Forming Reactions). An Overview (Masanam Kannan, Mani Sengoden and Tharmalingam Punniyamurthy) .21. Transition–Metal–Mediated Aromatic Ring Construction (Ken Tanaka) .22. Ar–C Bond Formation by Aromatic Carbon–Carbon ipso–Substitution Reaction (Maurizio Fagnoni and Sergio M. Bonesi) .Part 7. –H Functionalization .23. Chelate–Assisted Arene C–H Bond Functionalization (Marion H. Emmert and Christopher J. Legacy) .24. Reactivity and Selectivity in Transition Metal–Catalyzed, Non–Directed Arene Functionalizations (Dipannita Kalyani and Elodie Marlier) .25. C–H Bond Activation Catalysed by Transition Metal Complexes: Synergy between Experiment and Theory (Amalia Isabel Poblador Bahamonde) .Part 8. Directed Metalation Reactions .26. Directed Metalation of Arenes with Organolithiums, Lithium Amides, and Superbases (Frédéric Leroux and Jacques Mortier) .27. Deprotonative Metalation Using Alkali Metal–Non Alkali Metal Combinations (F Chevallier, Florence Mongin, Ryo Takita and Masanobu Uchiyama) .28. The Halogen–Metal Interconversion and Related Processes (M = Li, Mg) (Armen Panossian and Frédéric R. Leroux) .Part 9. hotochemical Reactions .29. Aromatic Photochemical Reactions (Norbert Hoffmann and Emmanuel Riguet) .30. Photochemical Bergman Cyclization and Related Reactions (Rana K. Mohamed, Kemal Kaya and Igor V. Alabugin) .31. Photo–Fries Reaction and Related Processes (Francisco Galindo, M. Consuelo Jiménez and Miguel Angel Miranda) .Part 10. Biotransformations .32. Biotransformations of Arenes. An Overview (Simon Lewis)

• ISBN: 978-1-118-75201-2
• Editorial: Wiley–Blackwell
• Encuadernacion: Cartoné
• Páginas: 992
• Fecha Publicación: 12/01/2016
• Nº Volúmenes: 1
• Idioma: Inglés