Enzyme Active Sites and their Reaction Mechanisms provides a one-stop reference on how enzymes work. Here, Dr. Harry Morrison, PhD and Professor Emeritus at Purdue University, provides a detailed overview of the origin and function of forty enzymes, the chemical details of their active sites, their mechanisms of action, and associated cofactors. The enzymes featured highlight a step forward, along with possible areas of application, thus supporting new research in academic and industrial labs. Each chapter is written in a clear format, including a brief summary of enzyme function and structure, a detailed description of their mechanisms of action and associated co-factors. Additionally, an introductory chapter describes the relationship between new and evolving experimental approaches (e.g. X-ray crystallography) and recent advances in our knowledge of enzyme active sites and their reaction mechanisms. Offers a comprehensive, biochemical understanding of enzyme mechanisms and their reaction sitesSupports new research in academic, medical and industrial labs, connecting discoveries powered by recent advances in technology and experimental approaches to areas of applicationFeatures short, carefully structured, actionable chapters on various enzyme classes, thus allowing for easy-use and searchability INDICE: 1. Acetylcholinesterase2. Aconitase3. Adenosine deaminase4. Alcohol dehydrogenase5. Aldehyde dehydrogenase6. Arginase7. Carbonic anhydrase8. Carboxypeptidase A9. Chymotrypsin10. Citrate synthase11. Cytochrome P450cam12. m5C Cytosine methyltransferase13. Deoxyribodipyrimidine photolyase14. Dihydrolipoamide dehydrogenase15. Dihydrolipoyl transacetylase16. Farnesyl pyrophosphate synthase17. Fructose-1,6-bisphosphate aldolase18. Hepatitis C NS2/3 protease19. HIV-1 protease20. Indoleamine-Dioxygenase-121. Lysozyme22. Methyl-coenzyme M reductase23. Methylmalonyl CoenzymeA Mutase24. Non-heme iron halogenase25. Peptidylarginine deiminase26. Peptidylglycine a-hydroxylating monooxygenase27. Phenylalanine hydroxylase28. Phosphatidylinositol-specific phospholipase C29. Protein kinase A30. Pyruvate carboxylase31. Pyruvate dehydrogenase32. Ribonucleotide reductase33. Ribonuclease A34. Serine racemase35. Soluble quinoprotein glucose dehydrogenase36. Tetrachloroethene reductive dehalogenase37. Thymidylate synthase38. 20S Proteasome39. Uracil-DNA Glycosylase40. Vanadium-dependent chloroperoxidase
- ISBN: 978-0-12-821067-3
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 264
- Fecha Publicación: 01/12/2020
- Nº Volúmenes: 1
- Idioma: Inglés