Combinational Therapy in Triple Negative Breast Cancer discusses TNBC at the molecular level with a holistic approach, focusing on combinational strategies targeting various pathways involved in this specific cancer type. Using a monotherapy for the treatment of cancer, especially high-grade tumors like TNBC, is mostly worthless due to the inherent genetic instability of tumor cells to develop intrinsic and acquired resistance; combination therapy presents more, or at least the same, effectiveness with lower doses of every single agent and decreases the likelihood of chemoresistance, making essential to understand more about multiple therapies options. The book is a valuable resource for cancer researchers, oncologists, graduate students, and members of biomedical field who are interested in the potential of combinational therapies to treat triple negative breast cancer. Presents up to date and cutting-edge knowledge of Triple negative breast cancer (TNBC) biology, clinical aspects, and treatment options Discusses novel targets and pathways involved in TNBC Provides insights and approaches for future research on TNBC INDICE: 1. Triple-negative breast cancer: An aggressive subtype of breast cancer 2. Novel biomarkers in triple-negative breast cancer: Role and perspective 3. Current therapeutics and treatment options in TNBC 4. Conventional adjuvant chemotherapy in combination with surgery, radiotherapy and other specific targets 5. Role of immune system in TNBC 6. The interplay of immunotherapy, chemotherapy, and targeted therapy in TNBC 7. Targeting biologically specific molecules in TNBC 8. Different drug delivery approaches in combinational therapy in TNBC
- ISBN: 978-0-323-96136-3
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 300
- Fecha Publicación: 01/05/2022
- Nº Volúmenes: 1
- Idioma: Inglés