Factors Affecting Neurological Aging: Genetics, Neurology, Behavior, and Diet

Factors Affecting Neurological Aging: Genetics, Neurology, Behavior, and Diet is a comprehensive reference on the genetic and behavioral features associated with neurological aging and associated disorders. This book discusses the mechanisms underlying neurological aging and provides readers with a detailed introduction to the aging of neural connections and complexities in biological circuitries, as well as the physiological, behavioral, molecular, and cellular features of neurological aging. Finally, this comprehensive resource examines the use of animal modeling of aging and neurological disease. Provides the most comprehensive coverage on a broad range of topics related to the neuroscience of aging Features sections on the genetic components that influence aging and diseases of aging Focuses on neurological diseases and conditions linked to aging, environmental factors and clinical recommendations Includes more than 500 illustrations and tables INDICE: I. Genetics, Molecular and Cellular Biology 1. Genetics of frontotemporal dementia 2. Aging, brain-derived neurotrophic factor (BDNF) and its polymorphism 3. Aging, demented patients, and polymorphisms in cytokine genes 4. RNA fragments and brain aging 5. Centrosome functions and remodeling during neuronal development and centrosome abnormalities in neuronal disorders, disease, and in aging 6. Brain aging and microarray analysis 7. Human nuclear tau and aging 8. Lipoxidation: features, neurological tissues and aging 9. Aging and brain amino acids 10. How 3',5'-cyclic nucleotide phosphodiesterases change in the brain with normal aging and dementia 11. The prohibitin complex in aging and neurodegeneration 12. Synaptic ATPase and energy metabolism in the nervous system: roles and changes in the aging process II. Neurological and Imaging Features 13. Microstructural Imaging of the Human Brain with Normal and Abnormal Aging using Diffusion Magnetic Resonance Imaging 14. Imaging the brain and its vascular in aging: Applications of optical coherence tomography angiography 15. Potential involvement of perineuronal nets in brain aging: an anatomical point of view 16. Grey-matter networks in aging 17. Brain synapse-related proteins what they do and how they change in aging 18. Macro- and chaperone-mediated autophagy in aging 19. Neuronal L-type calcium channels in aging 20. D-serine-regulated glutamatergic transmission and microglia: impact of aging 21. Voltage-gated potassium channels and the aging brain 22. Dendritic spine remodeling and aging 23. High-density lipoprotein-cholesterol and neuroaging: memory, gyrification of the insular and frontal opercular cortex 24. Astrocyte and microglial aging: morphology and modelling 25. Neural scaffolding: features, profiles and the aging cerebellum 26. BACE1 RNAi, memory and aging 27. Aging, myelination and the optic nerve 28. Linking proteostasis, brain aging, and ischemia 29. Luteinizing hormone and the aging nervous system 30. Insights into aging using transcranial magnetic stimulation 31. Alpha rhythms: what they are and how they alter with aging 32. Nicotine and its derivatives in healthy brain aging III. Physiological Aspects 33. Environmental enrichment and physiological aging 34. Treadmill exercise and neuroinflammation: links with aging 35. Impact of aerobic exercise on brain structure in models of aging: hippocampus and beyond 36. The physiology of fitness and the brain in aging 37. Aging, Babble Noise and the processing of speech perception 38. The blood-brain barrier in aging IV. Behavior And Psychopathological Aspects 39. Linking aging, anticholinergic drug use, and cognitive impairment 40. Cognitive Frailty: Definition, components and impact on disability, and mortality 41. The physiology of the Brain-muscle loop in aging 42. Disentangling the effects of aging and ovarian hormone loss on sleep: Implications for health and disease 43. Role of DNA methylation in aging-related cognitive functioning' 44. Depression in the elderly and psychobiotics V. Diet And Nutrition 45. Aging, dietary patterns and cognition 46. Geriatric nutritional risk index: Application, and limitations 47. Diet, inflammatory biomarkers, and brain aging 48. DASH diet and brain aging 49. The ketogenic diet and healthy brain aging 50. Autophagy and aging: diet, exercise, and the link with the target of rapamycin complex 1 (TORC) 51. Dietary Flavonoids and Brain Health in Ageing: food for Thought 52. Antioxidant effects of curcumin and neuroaging 53. Lipoic acid and vitamin D3 and their use in preventing brain aging 54. Aging and working memory: Impact of the leucine metabolite beta hydroxy-beta-methyl butyrate 55. Hydration, the brain and aging

• ISBN: 978-0-12-817990-1
• Editorial: Academic Press
• Encuadernacion: Cartoné
• Páginas: 686
• Fecha Publicación: 12/07/2021
• Nº Volúmenes: 1
• Idioma: Inglés