We visualise developmental biology as the study of progressive changes that occur within cells, tissues and organisms themselves during their life span. A good example of a field of developmental biology in which this concept is encapsulated is that of somitogenesis. The somite was identified as the primordialunit underlying the segmented organisation of vertebrates more than two centuries ago. The spectacular discoveries and achievements in molecular biology inthe last fifty years have created a gene-based revolution in both the sorts of questions as well as the approaches one can use in developmental biology today. Largely as a result of this, during the 20th and 21st centuries this simple structure, the somite, has been the focus of a deluge of papers addressing multiple aspects of somite formation and patterning both at the cellular and molecular level. INDICE: Formation and Differentiation of Avian Somite Derivatives.- Avian Somitogenesis: Translating Time and Space into Pattern.- Genetic analysis of somite formation in laboratory fish models.- Old wares and new: five decades ofinvestigation of somitogenesis in Xenopus laevis.- Role of Delta-Like-3 in Mammalian Somitogenesis and Vertebral Column Formation.- Mesp-Fa mily Genes are Required for Segmental Patterning and Segmental Border Formation.- bHLH Proteins and Their Role in Somitogenesis.- Mouse Mutations Disrupting Somitogenesis and Vertebral Patterning.- Defective Somitogenesis and Abnormal Vertebral Segmentation in Man.- Index.
- ISBN: 978-0-387-09605-6
- Editorial: Springer
- Encuadernacion: Cartoné
- Páginas: 210
- Fecha Publicación: 01/02/2009
- Nº Volúmenes: 1
- Idioma: Inglés