Topical Dermal Drug Delivery: Concepts and Advances

Topical Dermal Drug Delivery: Concepts and Advances compiles, in a single volume, the most recent advances in topical and dermal formulations for the treatment of skin disorders. The book covers three major concepts. The skin anatomy and physiology part includes chapters focused on relevant information for drug delivery. The second part of the book deals with several recent topical dermal drug delivery systems, including computational methods, permeation enhancers, bio precursors, hydrogels, emugels, exosomes and several nanotechnology enabled systems. The third and final part covers scaling up, toxicity, clinical trials, and regulatory considerations. This is a complete reference for academic and corporate pharma researchers investigating targeted drug delivery to the skin. Medical & Health Sciences researchers would also benefit from understanding the delivery systems covered in this book. Includes coverage of skin structure, physiology, pharmacology, and skin disordersCovers updated methods and techniques for the customization of novel topical dermal drug delivery systemsProvides a comprehensive compilation of marketed and clinical trials of novel topical dermal drug delivery systems INDICE: 1. Anatomy, Physiology and Immunology of Skin: What to know? 2. An Introduction to Skin diseases: Pathology and Therapeutics 3. Topical dermal drug delivery systems: Conceptualization and advancements 4. Dermatopharmacokinetic: Assessment tools for topically applied dosage forms 5. Artificial Intelligence, Machine learning, and Pharmacoinformatics: A headway to topical dermal drug delivery 6. Permeation enhancers for topical dermal drug delivery 7. Film forming topical dermal drug delivery systems: Basics and advances 8. Prodrug and bioprecursors for topical dermal dug delivery 9. Hydrogels and self-healing hydrogels for topical dermal drug delivery: Journey from bench to market 10. Emulgel: An integrated novel drug delivery system 11. Liposomes as topical dermal drug delivery systems: Lab to bedside 12. Niosomes for topical dermal drug delivery: Preclinical and clinical milestones 13. Transfersomes for topical dermal drug delivery: A matchless carrier 14. Polymersomes for topical dermal drug delivery: Basic views and advancements. 15. Phytosomes for topical dermal drug delivery: Concept and advances 16. Exosomes for topical dermal drug delivery: Recent progress and future Perspectives 17. Polymeric micelles for topical dermal drug delivery: Design, synthesis and applications 18. Lipid nanoparticles for topical dermal drug delivery: Preclinical and clinical advances 19. Polymeric nanoparticles for topical dermal drug delivery: Design and applications 20. Polymeric microparticles for topical dermal drug delivery 21. Dendrimers for topical dermal drug delivery: Recent progress 22. Non-invasive approaches for skin delivery 23. RNA therapeutics for topical dermal drug delivery: From bench to benchside 24. Topical immunization for skin disorders 25. Toxicological considerations of novel topical dermal drug delivery systems 26. Scale up and clinical translation of topical dermal drug delivery products 27. Regulatory framework for development of novel topical dermal drug delivery systems

• ISBN: 978-0-443-21945-0
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 600
• Fecha Publicación: 01/12/2024
• Nº Volúmenes: 1
• Idioma: Inglés