This concise introductory textbook uses carefully chosen examples from clinical and experimental observations to provide an insight into the principles underlying the immune system. As a result, it encourages readers to ask critical questions in order to further advance our understanding of this unique organ. Both authors are experienced lecturers and highly regarded researchers. INDICE: INTRODUCTION TO IMMUNOLOGY Introduction Immune responses Infectionand immunity Immunopathology and immunotherapy Thinking about immunology THE IMMUNE SYSTEM Introduction Host defence against infection The anatomical basisof immunity The cellular basis of immunity The molecular basis of immunity Immune responses and disease Learning outcomes INFECTION AND IMMUNITY Introduction Pathogens and infectious disease Host defence against infection Infection and immunity in action Immunity and vaccines Learning outcomes Questions and answers FUNCTIONAL ANATOMY OF THE IMMUNE SYSTEM Introduction Natural barriers Functional anatomy of innate immunity Functional anatomy of adaptive immunity Development of blood cells and organs of immunity Stem cell and gene therapy Learning outcomes Questions and answers Further Study Questions INNATE IMMUNITY Introduction Induction of innate immunity 'Tissue-resident cells' of innate immunity Recruited effectors of innate immunity Haematopoiesis and myeloid cells Vaccines and adjuvants Learning outcomes Questions and answers Further Study Questions T CELL-MEDIATED IMMUNITY Introduction The Major Histocompatibility Complex (MHC) Antigen presentation The anatomical basis of T cell responses T lymphocyte activation Effector and memory functions of T cells in infection T cell development & selection Adoptive cell therapy Learning outcomes Questions and answers Further study questions ANTIBODY-MEDIATED IMMUNITY Introduction Antibody structure and function B cell responses B cell memory, antibodies, and long-term resistance to re-infection B cell differentiation and selection Therapeutic antibodies Learning outcomes Questions and answers Further study questions IMMUNITY, DISEASE AND THERAPY Introduction What are the mechanisms of tissue damage caused by the immune system? Why do we make harmful immune responsesto 'harmless? antigens? Immunopathology and therapy in action Transplantationimmunology Tumour immunity Conclusions Learning outcomes Questions and answers
- ISBN: 978-3-527-32430-9
- Editorial: Wiley-VCH
- Encuadernacion: Cartoné
- Páginas: 334
- Fecha Publicación: 11/01/2012
- Nº Volúmenes: 1
- Idioma: Inglés