The first complete reference on this growing field in the biosciences covers the full spectrum of current concepts, methods and application areas in two massive volumes. Highly useful for protein engineers in academia and industry alike. INDICE: PART 1: FUNDAMENTALS OF PROTEIN ENGINEERING Historical perspectiveStructure and function in proteins Protein engineering and dynamics Evolution: Protein engineering in Nature Metagenomics and genome prospection Engineering the reaction environment Patents and legal aspects PART 2: PROTEIN ENGINEERING METHODS In silico protein design Rational protein engineering Protein evolution in the laboratory Selection and screening In situ directed evolution Library evaluation Production scale biosynthesis PART 3: APPLICATIONS OF PROTEIN ENGINEERING Antibody engineering Engineering secondary metabolism Pathway engineering and multienzyme systems Engineering thermostability Novel enzyme functions Engineering substrate specificity Introducing unnatural amino acids Glycosylation engineering Inteins in protein engineering Biosensors and regulators Protein folding Plant proteins Biomaterials
- ISBN: 978-3-527-31850-6
- Editorial: Wiley-VCH
- Encuadernacion: Cartoné
- Páginas: 1015
- Fecha Publicación: 12/11/2008
- Nº Volúmenes: 2
- Idioma: Inglés