DNA Interactions with Polymers and Surfactants provides a broad overview of the interaction of DNA with cosolutes in both bulk solution and at interfaces. It provides the basis for understanding the factors leading to complexation between DNA and different cosolutes as well as DNA adsorption at different interfaces. This book also covers DNA-cosolute interactions including simple metal ions, polyelectrolytes, spermine, spermidine, surfactants and lipids, and proteins. INDICE: 1. Polyelectrolytes. Physico-Chemical Aspects and Biological Significance. 2. Solution behavior of nucleic acids. 3. Single DNA molecules: Compaction and decompaction. 4. Interaction of DNA with surfactants in solution. 5.Interaction of DNA with cationic polymers. 6. Interactions of Histones with DNA: Nucleosome Assembly, Stability, Dynamics and Higher Order Structure. 7. Opening and closing DNA: theories on the nucleosome. 8. DNA-DNA interactions. 9.The hydration of DNA - amphiphile complexes. 10. Interfacial DNA-surfactant/lipid complexes at liquid interfaces. 11. Adsorption of DNA and DNA-surfactant complexes at solid surfaces. 12. The role of correlation forces for DNA-cosolute interactions. 13. Simulations of polyions: compaction, adsorption onto surfaces, and confinement. 14. Cross-linked DNA Gels and Gel Particles. 15. DNA asan amphiphilic polymer. 16. Lipid?DNA Interactions: Structure?Function Studies of Nanomaterials for Gene Delivery.
- ISBN: 978-0-470-25818-7
- Editorial: John Wiley & Sons
- Encuadernacion: Cartoné
- Páginas: 432
- Fecha Publicación: 16/05/2008
- Nº Volúmenes: 1
- Idioma: Inglés