As haemophilia is life-long, continuing supervision by a group of medical personnel is desirable. In many countries this is provided by comprehensive care haemophilia centers where staff of all specialities concerned with treatment- haematologists, paediatricians, nurses, physiotherapists, orthopaedic surgeons- have specialized knowledge. The Textbook of Hemophilia has become the definitive resource on all aspects of haemophilia including diagnosis, management and treatment. It covers all the common and rare bleeding disorders, both in terms of clinical management as well as the genetic, laboratory, financial and psychological aspects. Complications of haemophilia care are well covered in chapters on inhibitors, musculoskeletal problems and transfusion-transmitted disease. This new edition includes all the latest developments in the field of haemophilia. The book is divided into 19 major sections. It begins with an overview of haemostasis and cellular processing of factors, then gives guidance on how to assess both bleeding children and adults. Both Haemophilia A and B are discussed in detail and there is coverage of the molecular basis of the disease, the role of factors in coagulation, epidemiology, pharmacokinetics, and treatment of inhibitors. There is also a section on musculoskeletal aspects of haemophilia as apart from bruising, haemorrhages into the joints are the most common feature of the condition. The current products used to treat haemophilia are covered, specifically recombinant factor and plasma-derived factor. Newer developments such as gene therapy and the molecular engineering of these factors are addressed. A section is dedicated to the rare bleeding disorders and the book concludes with chapters on comprehensive care and its delivery worldwide.
- ISBN: 978-1-4051-6914-1
- Editorial: Wiley-Blackwell
- Encuadernacion: Cartoné
- Páginas: 476
- Fecha Publicación: 18/06/2010
- Nº Volúmenes: 1
- Idioma: Inglés